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Increasing the amount of action potentials that arrive at the presynaptic terminal will:
Correct Ans-Increase the amount of depolarization in the terminal
Increase the amount of Ca2+ that enters the presynaptic terminal.
Increase the number of vesicles that fuse with the presynaptic membrane
Increase the amount of neurotransmitter released.
What would happen if we reduced the acetylcholinesterase in the synaptic cleft? Correct
Ans-We would have more ACh in the cleft.
The ACh in the cleft would remain in the cleft for a longer period of time.
We would have greater postsynaptic potentials generated.
WHY? >>
, Exam- BIPN 100 Quizes; Questions and Answers Rated
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Reducing the amount of ACh-ase would result in less ACh breakdown, so there would be more
ACh in the cleft. Since it takes time for the remaining ACh-ase to breakdown ACh, the ACh
would stay in the cleft for a longer period of time, too.
Increasing the amount and duration of NT would increase the magnitude of postsynaptic
effects because presumably we'd be activating more receptors for a longer period of time.
forskolin is a drug used by scientists to render adenylyl cyclase (AC) constitutively (always)
active. What will this do to:
a) PKA levels?
b) IP3 levels? Correct Ans-a) increase PKA
b) no effect on IP3
A postsynaptic potential is excitatory (EPSP) if the ion involved has a reversal potential (Eion)
that is more depolarized than the resting membrane potential (Vm or Vrest), even if that Eion
is hyperpolarized to the threshold for firing an action potential. Correct Ans-False