PMCOL 343 1 EXAM LATEST UPDATE

PMCOL 343 1 EXAM LATEST
UPDATE

BOTOX -Answer blocks vesicle fusion and Ach release

A-methyltyrosine -Answer inhibits tyrosine conversion to L-DOPA

Cocaine/tricyclic antidepresant -Answer prevent reuptake of NA

Choline esters -Answer Acetylecholine, carbachol, bethanechol

M agonist -Answer muscarine, oxotremorine, pilocarpine

Anticholinesterase -Answer edrophonium, neostimine, malathion, soman

edrophonium -Answer simple alchohol

neostigmine -Answer carbamic ester

Malathion -Answer insecticide

Soman -Answer nerve gas

therapeutic uses of cholinomimetics -Answer glaucoma, urinary retention,
postoperative ileus, M gravis

Nicotinic antagonists -Answer succinylcholine, D-tubocurarine, a-bungarotoxin

Succinylcholine -Answer paralysis during surgery

D-tubocurarine -Answer causes depolarizing neuromuscular blockade

M antagonists -Answer Atropine, scopolamine, ipratropium

Scopolamine -Answer vestibular disturbances

Ipratropium -Answer COPD

Gq acting -Answer M1, M3, a1, H1

Gs acting -Answer B, adenosine 2, H2

Gi acting -Answer a2, CB1, H3, adensoine1/3

Tyramine -Answer indirectly acting sympathomimetic.

induces catecholamine release. Normally metabolized by MAO