NUR 265 NEURO QUESTIONS & ANSWERS, SOLVED 100% CORRECT!!

most common form; with each relapse, recovery is complete but residual deficits accumulate over time - relapsing-remitting meds for fatigue (4) - amantadine (symmetrel) pemoline (cyclert) methylphenidate (ritalin, concerta) modafinil (provigil) MS affects - 20-40 year old women disease progression with or without relapses - secondary progressive disabling symptoms steadily increase with rare plateaus and temporary improvement - primary progressive least common; relapses with continuous disabling progression between exacerbations - progressive relapsing diagnostic tests for MS (4) - exam MRI EPS (evoked potential studies) CSF (identifies presence of oligoclonal banding) disease-modifying meds - A - Avonex (IM once per week) OR Rebif (SQ 3 times per week) B - Betaseron (SQ every other day) C - Copaxone (SQ daily)disease-modifying med goals (3) - decrease frequency of relapse decrease duration of relapse decrease plaques on MRI BRM side effects (5) - flu-like - take at night depression/suicidal tendencies/anxiety leukopenia/thrombocytopenia elevated liver enzymes hypersensitivity at injection site copaxone side effect - transient chest pain things to monitor when on BRMs (4) - liver enzymes CBC/platelets injection site emotional changes Multiple Sclerosis is an ___ mediated, progressive ___ disease of the CNS that results in impaired ___ ____ - immune, demyelinating, nerve transmission cytoxan and methotrexate are ___ agents - antineoplastic immuran and sandimmune are ____ drugs - immunosuppressant anticonvulsant drug for spasticity - klonopin med for acute relapse...dosage - IV methylprednisone 1g daily for 3-5 days with or without PO prednisone taper OR ACTH - stimulates release of cortisol; 25-60 mg over 2-4 weeksOR oral prednisone 60 mg for 5-7 days IV infusion given every 3 months to reduce frequency of relapse - Novantrone novantrone side effect - cardiotoxicity...pt can only have 140 mg/m2 in a lifetime primary med for spasticity....antispasmotic - baclofen (lioresal) tranquilizer - benzodiazepine (valium) antispasmotic - tizanidine (zanaflex) muscle relaxer - dantrolene (dantrium) med for UTI - absorbic acid (vitamin c) meds for bladder dysfunction (4) - ditropan & pro-banthine - anti-cholinergic/-spasmotic anaspaz, cytospaz desmopressin - ADH urecholine - cholinergic for retention