Exam (elaborations)

APHA NAPLEX 2024 STUDY GUIDE QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

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APHA NAPLEX 2024 STUDY GUIDE QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

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NAPLEX

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NAPLEX

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Institution: NAPLEX
Course: NAPLEX

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Uploaded on: September 8, 2024
Number of pages: 16
Written in: 2024/2025
Type: Exam (elaborations)
Contains: Questions & answers

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apha naplex 2024 study guide questions and answers

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APHA NAPLEX 2024 STUDY GUIDE
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
VolumeIofIDistributionI-IANSWERIamountIofIdrugIinItheIbody/concentrationIofIdrugIinIplasma

Lipophilicity--I-IANSWERIhighIlipophilicityIincreasesIpassageIintoItissues

MolecularIweight---I-IANSWERIlowImolecularIweightIallowsIdrugsItoIpassImembranesIeasier

Ionization--I-IANSWERIun-ionizedIdrugsIhaveIincreasedIdistribution

ProteinIbinding--I-IANSWERIlowIproteinIbindingIinIbloodIisIimportantIforIincreasedIdistribution

Membranes--I-IANSWERIincreasedImembraneIpermeabilityIincreasesIdistributinoIintoItissues

InDucers--I-IANSWERIDecreaseIdrugIlevels:IprodrugsIinducersIincreaseIlevelsIofItheIactiveIform

Ultra-metabolizersIhaveIsameIeffectIonIdrugIlevels

INhibitors--I-IANSWERIINcreaseIdrugIlevels:IprodrugsIinhibitorsIdecreaseIlevelsIofIactiveIform

PoorImetabolizersIhaveIsameIeffect

ClearanceI-IANSWERIkeIXIVd

CommonIInducersI-IANSWERISUPERICOPS

Smoking,IU,IPhenytoin,IE,IRifampin,ICarbamazepine,IOxcarbezepine,IPhenobarbital,ISt.IJohn'sIWort

CommonIInhibitorsI-IANSWERICAMPAIGN

Cimetidine,IAzoles,IMacrolides,IProteaseIinhibitors,IAmiodarone,II,IGrapefruit,INon-DHPICCB

,Half-LifeI-IANSWERI0.693/ke--itItakesI5IhalfIlivesItoIreachIsteadyIstate

IVIloadingIdoseI-IANSWERIdesiredIconcentrationIXIVd/F

Non-IVIloadingIdoseI-IANSWERImaintenanceIdoseIXIRaI(accumulationIfactor)

WhatIareItheI5IGsIandIwhatIdoItheyIincreaseItheIriskIof?I-
IANSWERIGarlic,IGinkgo,IGinger,IGinseng,IGlucosamine--increaseIbleedingIrisk

PercentageIorIratioIstrengthI-
IANSWERIJustItakeIwhatIeverIyouIhaveIandIthenIdoI100/thatInumberItoIgetItheIother

PPMIfromIpercentageIstrengthI-IANSWERIMoveItheIdecimalIleftI4Ispots

PercentageIstrengthIfromIPPMI-IANSWERIMoveItheIdecimalIrightI4Ispots

SpecificIgravityI-IANSWERIg/mL

mOsmol/LI-IANSWERIweightIofIsubstance/MWIXInumberIofIparticlesIXI1000

molsI-IANSWERIg/MW

mmolsI-IANSWERImg/MW

mEqI-IANSWERImgIXIvalence/MW

DextroseI-IANSWERI3.4Ikcal

, ProteinI-IANSWERI4Ikcal

FatI10%I-IANSWERI1.1Ikcal

FatI20%I-IANSWERI2Ikcal

DailyIFluidIGoalI-IANSWERIIfIweightIisI>I20Ikg:I1500ImLI+I20Iml(weightI-20)

GoodIindicatorIofIdehydrationI-IANSWERItheIBUN:SCr>20:1

CorrectedICalciumI-IANSWERIMeasureIcalciumI+I0.8(4-albumin)

CalciumIandIphosphateIreplacementI-
IANSWERIAddIphosphateIthenIcalcium,IuseIcalciumIgluconateIversusIcalciumIchloride,IthemIaddedItogetherI

shouldInotIexceedI45ImEq/L

BMII-IANSWERIlb/inches^2IX703

IBWIfemalesI-IANSWERI45.5+2.3(inchesIoverIfiveIft)

AdjBWI-IANSWERIIBW+0.4(actualIBW-IBW)

CrCLI-IANSWERI140-ageIXIwt/72IXISCr....XI0.85IifIfemale

AnionIGapI-IANSWERINa-Cl-HCO3

ANCI-IANSWERIWBCIXI(segI+Ibands)/100

FurosemideItoIbumetanideI-IANSWERI40:1

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APHA NAPLEX 2024 STUDY GUIDE QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

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