NAPLEX PRACTICE QUESTIONS -CARDIOVASCULAR CONDITIONS QUESTIONS AND ANSWERS WITH SOLUTIONS 2024

NAPLEX PRACTICE QUESTIONS -
CARDIOVASCULAR CONDITIONS
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
AllAofAtheAfollowingAareAantiplateletAagentsAthatAcanAbeAusedAinAtheAtreatmentAofAanAacuteAcoronaryAsynd
romeAEXCEPT:



A.AClopidogrel

B.ADalteparin

C.AEptifibatide

D.ATicagrelor

E.AAspirinA-AANSWERAB.ADalteparin



Aspirin,AP2Y12AinhibitorsAandAglycoproteinAIIb/IIIaAreceptorAantagonistsAcanAbeAgloballyAcalledA"antiplatel
etAagents"AbasedAonAtheirAmechanismsAofAaction.ADalteparinAisAanAanticoagulant.



DLAisAaA77-year-
oldAmaleA(6'3",A315Apounds)AwhoApresentsAtoAtheAemergencyAdepartmentAwithAaASTEMI.AHeAwasAgivenAas
pirinA325AmgAinAtheAfieldAandAwasAstartedAonAaAnitroglycerinAdripAatA100Amcg/min.AHisAoxygenAsaturationAi
sA94%AandAheAhasAreceivedAmorphineAsulfateA2AmgAIVA×A2AandAmetoprololA5AmgAIAinAtheApastA30Aminutes.A
HisAbloodApressureAisA164/101,AHRAisA95Abpm,AandAhisArespiratoryArateAisA22Abpm.AWhichAofAtheAfollowingA
medicationsAshouldANOTAbeAgivenAtoAtheApatientAdueAtoAincreasedAmortality?



A.ANifedipineAimmediate-release

B.ATorsemide

C.ACandesartan

D.ADiltiazemAextended-release

E.AEnalaprilA-AANSWERAA.ANifedipineAimmediate-release



Immediate-releaseAnifedipineAisAassociatedAwithAincreasedAmortalityAwhenAusedAinAtheAacuteAsetting.

,WhatAisAtheAprimaryAreasonAforAusingAaspirinAinAaApatientAwithAchestApain?



A.AInhibitAplateletAaggregation

B.AProvideAmoderateAdegreeAofAanalgesia

C.AIncreaseAmortalityAinApatientsAwithASTEMI

D.APreventAflushing

E.ABreakAdownAtheAclotA-AANSWERAA.AInhibitAplateletAaggregation



AspirinAinhibitsAplateletAaggregation,AstabilizesAplaqueAandAhelpsAtoAarrestAthrombusAformation.

AspirinAdoesAnotAbreakAdownAtheAexistingAclot,AbutAratherApreventsAitAfromAenlargingAandAprogressing.AAs
pirinAprovidesAveryAmildAanalgesiaAandAisAnotAusedAforAanalgesiaAinApatientsAwithAchestApain.



AApharmacistAcoveringAtheAemergencyAdepartmentAreceivesAanAorderAforAtissueAplasminogenAactivatorA(t
PA)A15AmgAIVAbolus,A50AmgAoverA30Amin,AthenA35AmgAoverA1Ahour.ATotalAdoseA=A100Amg.AWhatAdrugAisAbei
ngAordered?



A.AAbciximab

B.AAlteplase

C.AEpitifibatide

D.ATenecteplase

E.ATirofibanA-AANSWERAB.ALateAplease



AlteplaseA(Activase)AisArecombinantAtissueAplasminogenAactivatorA(rtPAAorAsimpleA"(PA").

CorrectAdosingAisAcriticalAdueAtoAbleedingArisk.ATheAacceleratedAinfusionAdosingAforASTEMIAdiffersAfromAthe
ArecommendedAdoseAforAacuteAischemicAstrokeA(seeAStrokeAchapter).




AHAisAbeingAdischargedAfromAtheAhospitalAafterAaAmyocardialAinfarction.ATwoAbare-
metalAstentsAwereAplacedAyesterday.AUponAdischarge,AheAwillAcontinueAtakingAhisAPrasugrelAtherapyAwhic
hAwasAstartedAyesterday.AWhatAisAtheAminimumAperiodAofAtimeAthatAAHAwillAneedAtoAtakeAPrasugrel?

,A.A6Amonths

B.A1Ayear

C.A2Ayears

D.A3Ayears

E.AIndefinitelyA-AANSWERAB.A1Ayear



AfterAanAMI,ApatientsAshouldAreceiveAaspirinAandAaAP2YA12AinhibitorAforAaAminimumAofA12Amonths.

TheAminimumArecommendationAisAtheAsameAforApatientsAmanagedAmedicallyAorAforAthoseAstented.



WhichAofAtheAfollowingAmedicationsAshouldAbeAavoidedAinAaApatientApresentingAwithAACS?



A.AMetoprolol

B.ALisinopril

C.ACelecoxib

D.AAspirin

E.AEnoxaparinA-AANSWERAC.ACelecoxib



NSAIDsA(exceptAaspirin),AregardlessAofACOXAselectivity,AshouldAbeAavoidedAinApatientsAwithAACS.AIfAsaferAag
entsA(acetaminophen,Atramadol,AsmallAdosesAofAopioids)AareAnotAeffective,AnaproxenAisAgenerallyAconside
redAtoAhaveAtheAlowestAcardiovascularAriskA(butAthereAisAstillArisk).



WhichAofAtheAfollowingAareAlikelyAsigns/symptomsAofAaAheartAattack?A(SelectAALLAthatAapply.)



A.AChestApainAorApressureAthatAlastsAmoreAthanAaAfewAminutes

B.AShortnessAofAbreath

C.AIncontinence

D.ASweating

E.ASeizure

F.ARadiatingApainA-AANSWERAA.AChestApainAorApressureAthatAlastsAmoreAthanAaAfewAminutes

, B.AShortnessAofAbreath

D.ASweating

F.ARadiatingApain



ManyAmyocardialAinfarctionsAinvolveAchestAdiscomfortAthatAlastsA10AminutesAorAmore,AorAthatAgoesAawayA
andAcomesAback.ATheApainAcanAradiateAforAextend)AtoAoneAorAbothAamAtheAbackAneck,AjawAorAstomachAand
AmayAbeAdesoribedAasA"squeezing"AorA'ressure",AShortessAofAbreathA(dyspnea)AandAsweatingA(diaphoresis)

AmayAalsoAoccur.




SRAisAaA61-year-
oldAfemaleA(5'3",A115Apounds)AwhoApresentsAtoAtheAemergencyAdepartmentAwithAaANSTEMI.AHerApastAme
dicalAhistoryAisAsignificantAforAdiabetes,Ahypertension,AmultipleATIAsAandAaAhipAfracture.ASheAwasAgivenAas
pirinA325AmgAinAtheAfieldAandAwasAstartedAonAaAnitroglycerinAdripAatA50Amcg/min.AHerAoxygenAsaturationAi
sA93%AandAsheAhasAreceivedAmorphineAsulfateA1AmgAIVAxA1AinAtheApastA30Aminutes.ASheAisAtransferredAtoAt
heAcardiacAcatheterizationAlaboratoryAandAangiographyAconfirmedAanA85%AblockageAofAherAleftAmarginalAa
rtery.ATheAcardiacAinterventionalistAwantsAtoAstartAaAP2Y12AinhibitorApriorAtoAtheAPCI.AWhichAmedicationAis
Aappropriate?




A.AActivase

B.AEffient

C.ALovenox

D.ABrilinta

E.ATNKaseA-AANSWERAD.ABrilinta



ThisApatientAhasAaAcontraindicationAtoAtheAuseAofAEffientA(historyAofATIA/stroke).AActivase,ATNKaseAandALov
enoxAdoAnotAworkAbyAP2YA12Ainhibition.



AApatientApresentingAwithAchestApainAunderwentAaAprocedureAtoAopenAaAcoronaryAartery,AThisAwasAdoneA
byAinflatingAaAsmallAballoonAinsideAtheAarteryAandAthenAplacingAaAstentAafterwardAtoAkeepAtheAarteryAopen
.AWhatAprocedureAdidAthisApatientAhaveAdone?



A.ACABG

B.AComputedAtomography