NAPLEX PRACTICE QUESTIONS AND ANSWERS

NAPLEX PRACTICE QUESTIONS AND
ANSWERS

Whattistthetrangetfortacutetmanictepisodettreatmenttwithtlithium?t-tans✔✔0.8-1.2tmEq/L

highertthantmaintenancettreatment

Whichtmedicationtmaytpotentiallytinteracttwithtandtraisetlithiumtlevels?
A.tmetoprolol
B.tlisinopril
C.tTenormin
D.tAPAPt-tans✔✔lisinoprilt

affectstthetkidneys!!

Whichtistatsideteffecttoftlithiumtthattcommonlytoccurstintpatientsttakingtlongtterm?
A.tataxia
B.tconstipation
C.thypothyroidism
D.tneuropathyt-tans✔✔C.thypothyroidismt

sometimes,tdiabetestinsipidius

whichtoftfollowingtisttruetregardingtMAOtinhibitorstfortdepression?
A.tpotentialtfortseveretsideteffectstofthypertensivetcrisistprecipitatedtbytcertaintfoods
B.tconsideredt1sttlinet
C.tgoodtchoicetbecausetfewtdrugtinteractionst-tans✔✔A.ttyraminet-
containingtfoodstcantprecipitatetSerotonintsyndrometandthypertensivetcrises

Whichtoftthetfollowingtagentstmaytbetconsideredt1sttlinetforttreatmenttoftmajortdepression?
A.tBuspar
B.tlithium
C.tfluoxetinet(Prozac)
D.tDoxepint(Silenor)t-tans✔✔Ctfluoxetinet
SSRIstandtSNRIstaretfirsttlinetfortdepression.t

Silenort=tinsomnia

,WhattistantadvantagetoftusingtbupropiontforttxtoftMDD?
A.tactiontistspecificttotserotonintunliketSSRIs
B.tfairlytsedatingtsotcantalsottreattinsomnia
C.tfreetfromteffecttoftloweringtseizuretthreshold
D.tfreetfromtsexualtsideteffectstunliketmanytSSRIst-
tans✔✔freetfromtsexualtsideteffectstunliketmanytSSRIs




**cantlowertseizuretthreshold

anothertbenefit:twellbutrintapprovedtfortsmokingtcessation

WhichtoftthetfollowingtaretcounselingtpointstfortpatienttswitchingtfromtSSRIt--
>tSNRItfortdepression?
A.tsametSEtastSSRIs,texcepttmaybetmoretHTN
B.tshouldtbetstoppedtabruptlytiftanytsideteffects
C.tmaytrequirettherapeutictdrugtmonitoringt-tans✔✔-tSametSEtastSSRIst
-tmaytincludetHTNt
-tdotnottstoptabruptlytwithoutttalkingttotDr.t
-tnotdrugtmonitoring

JS,taget56ttakesttamoxifentfortbreasttcancertremission.tStartingtSSRItfortMDD.tWhattistBES
Ttinitialtchoice?
A.tfluoxetine
B.tphenelzine
C.tPaxil
D.tZoloftt-tans✔✔D.tZoloft

fluoxetinetandtparoxetinetcantlowerttamoxifentlevelstintthetblood.

Whattaretthetgoalstofttherapytforttreatingtanxietytdisorders?
A.talleviatetalltsymptoms
B.timprovetfunctioningtintsociety
C.treducetanxioustsymptomstortpreventtrecurrence
D.timprovetoveralltqualitytoftmoodtandtsleept-
tans✔✔C.treducetsymptomstandtpreventtrecurrence




Whichtoftthetfollowingtwouldtbet1sttlinetfort35yotpatienttnewlytdiagnosedtwithtanxietyt(nototh
ertmeds)?
A.tCelexa
B.tOlanzapine
C.tBuspirone
D.tAtivant-tans✔✔Celexat(SSRItaretfirsttline)

Whattistthetroletoftbenzostinttxtoftanxiety?
A.tfirsttlinetfortnewlytdiagnosed

,B.tshortttermtfortinitialtperiodtoftSSRI
C.tPRNtbreakthroughtfortalltptstbeingttreatedtwithtmeds
D.ttxtoftchoicetfortpatientstwithtSUDt-tans✔✔B.tshortttermtfortinitialtperiodtoftSSRI

MUtistat38,tFtw/
tanxiety tdisorder.tShettriedtandtfailedt2tSSRIs,tbuttwaststillthavingtsignificanttanxietytsympto

ms.tMUthastathistorytoftdrugtabusetandtdependence.tShetwouldtlikettotresumettreatmenttfort
hertanxietyttoday.tWhichtoftthetfollowingttreatmenttoptionstwouldtbetmosttappropriatetforttre
atingtMU'stanxiety?
a.tLorazepamt
b.tParoxetinet
c.tZiprasidonet
d.tBuspironet-tans✔✔D.tbuspirone

At-tnotbecausethxtoftdrugtabuse
B.tnotbecausetSSRIsthavetfailedther
C.tZiprasidonetonlytindicatedtfortBPDtandtschizophrenia

Fortwhichtsymptomstoftschizophreniatmighttanti-psychotictmedstbetmostteffective?
A.tapathy
B.tsocialtwithdrawal
C.thallucinations
D.tflattaffectt-tans✔✔C.thallucinations

antipsychotictmedstonlyttreattPOSITIVEtsx,tnottnegative

Howtdotsideteffecttprofilestoft2ndtgentantipsychstcomparettot1sttgen?
A.t2ndtgentagentsttendttothavetlesstEPStthant1sttgentagents.t
B.t2ndtgent>>EPStthant1sttgen
C.t2ndtgent<<weighttgaintthant1sttgent
d.t2ndtgent>>TDtthant1sttgent-
tans✔✔2ndtgent(risperidone,tziprasidone,tquetiapine,tolanzapine,tabilify)t:

-tlesstEPS
-tlesstTD
-tmoretweighttgain/metabolictsyndrome

1sttgent(haldol):
-tmoretEPS/tTD
-tlesstweighttgain

WhichtoftthetfollowingtmedicationstcarriestantFDAtwarningstaboutthyperglycemiatandtdiabe
testrisktassociatedtwithtuse?t
a.tOlanzapinet
b.tHaloperidolt
c.tPerphenazinet
d.tFluphenazinet-tans✔✔A.tOlanzapinet(Zyprexa)t=t2ndtgen

, Whichtoftthetfollowingtisttruetregardingtthetusetoftclozapinetfortschizophrenia?t
a.tIttrequirestinitialtandtperiodictmonitoringtoftWBC.t
b.tItthastbeentshownttotbetequallyteffectivetastothertantipsychotics.t
c.tIttistconsideredtatfirsttgenerationtantipsychotic.t
d.tIttworkstbesttontthet"negative"tsymptomstoftschizophrenia.t-
tans✔✔Agranulocytosistcantoccurt=tcompletetwipetouttoftimmunetsystem.t




needttotbetintREMStprogramtandtgettbloodtworktbeforetdispensingtmeds

HallmarktfeaturestoftParkinson'stDiseaset(PD)tinclude:t
a.ttremortattresttandtbradykinesiatb.tshortnesstoftbreathtandtfacialtparalysist
c.tdepressiontandtinsomniat
d.tposturaltinstabilitytandtdizzinesst-tans✔✔tremortattrestt
bradykinesiat
reducedtspeechtvolume
posturaltinstabilityt(buttnottdizziness)

WhichtfeaturetoftPDtistlesstamenablettotmedicationttherapy?ta.ttremortattrestt
b.trigidityt
c.takinesiat
d.tposturaltimbalancet-tans✔✔posturaltimbalance

"Wearingtoff"teffecttistatphenomenontintPDtwhichtreferstto:t
a.twhentdopaminetagonistttherapeutictbenefittstopstpriorttotnexttdosetbeingtduet
b.twhentlevodopattherapeutictbenefittstopstpriorttotnexttdosetbeingtduet
c.twhentdopaminetagoniststbecometlesstreliabletinttheirttherapeutictactiontandtreturntoftPDts
ymptomstreturntintantunpredictabletmannertandtbenefittlaststonlytsecondsttotminutest
d.twhentlevodopatbecomestlesstreliabletintitsttherapeutictactiontandtreturntoftPDtsymptomstr
eturntintantunpredictabletmannertandtbenefittlaststonlytsecondsttotminutest-
tans✔✔b.twhentlevodopattherapeutictbenefittstopstpriorttotnexttdosetbeingtduet




"wearstoff"tpriorttotnexttdosetbuttstilltsometbenefittoccurs

"On/Off"teffecttistatphenomenontintPDtwhichtreferstto:t
a.twhentdopaminetagonistttherapeutictbenefittstopstpriorttotnexttdosetbeingtduet
b.twhentlevodopattherapeutictbenefittstopstpriorttotnexttdosetbeingtduet
c.twhentdopaminetagoniststbecometlesstreliabletinttheirttherapeutictactiontandtreturntoftPDts
ymptomstreturntintantunpredictabletmannertandtbenefittlaststonlytsecondsttotminutest
d.twhentlevodopatbecomestlesstreliabletintitsttherapeutictactiontandtreturntoftPDtsymptomstr
eturntintantunpredictabletmannertandtbenefittlaststonlytsecondsttotminutest-
tans✔✔d.twhentlevodopatbecomestlesstreliabletintitsttherapeutictactiontandtreturntoftPDtsy

mptomstreturntintantunpredictabletmannertandtbenefittlaststonlytsecondsttotminutes

thinktoftlightningtbugtgoingtontandtofft--unpredictableteffecttoftmeds