3/17/24, u10:19 POGIL u- uThe uCell uCycle
uPM uWorksheet
The Cell Cycle
u u
What ucontrols uthe ulife uand udevelopment uof ua
ucell?
Why?
An u old u piece u of u poetry usays u“to ueverything u there uis u a u season... u a u time u to ube u born, ua u time u to udie.”
u For u cells, uthe u line u might u say u “a u time u to u divide u and u a u time u to u grow.” u In u multicellular u organisms,
u different u types u of ucells uhave u different u roles u and uneed u to ucomplete u specific u tasks. u For uexample, u a
u cell uthat u isn’t u large u enough u is unot uuseful ufor ustoring unutrients ufor ulater, ubut ua ucell uthat uis utoo
ularge uwill unot ube uuseful ufor utransportation uthrough u a u tiny u capillary. u In u this u activity, u you u will
u learn u about u the u seasons u of u a u cell’s u life, u and u in u turn u better uunderstand uhow uorganisms ufunction.
Model u1 u– uThe uCell uCycle
G1
*
M Enters
(including ucytokinesis) uG0
G2
S
1. How u many u phases u are u in u the ucell u cycle u as u shown u in u the u diagram u in uModel u1?
4
2. Starting uat uthe ustarred ucell, uwhat uis uthe uorder uof uthe ustages uof ua ucell’s ulife?
G1,S,G2,M
3. During uwhich uphase udoes uthe usize uof uthe u cell u increase?
G1
4. During u which u phase u does u the u number u of u cells u increase?
M
The uCell uCycle 1
about:bla 1/6
nk
, 3/17/24, u10:19 POGIL u- uThe uCell uCycle
uPM uWorksheet
5. Considering uyour uanswer uto uQuestions u3 uand u4, uidentify utwo uways uthat uthe ugrowth uof uan
uorgan- uism ucan ube uaccomplished uthrough uthe uevents uof uthe ucell ucycle.
The ucells ucan ucontinue umultiplying u"endlessly", uresulting uin uthe ugrowth uof uthe uorganism uand
uthe ucells ucould ualso ugrow ufrom uG1.
6. Cancer, uthe uuncontrolled ugrowth uof ucells, uoften uresults uin ua utumor, uor umass uof
uabnormal ucells. uSome u cancerous u tumors u consist u of u many u cells u that u are u much u smaller
u than u normal. u According u to uModel u1, uwhat upart(s) uof uthe ucell ucycle uis u(are) umost ulikely
ubeing uaffected?
G1
7. In uModel u1, uif uthe ulength uof uthe uarrow urepresents utime, uthen ufor uthose ucancerous ucells,
uwhat uhap- upens uto uthe utime uthat uis unecessary ufor uthe ucell ucycle? uWhat uimplication umight
uthis uhave ufor udoctors uwho uare utreating ucancer upatients?
G1 uis uwhere uthe ucell uwill uspend uthe umost uamount u of utime.
Model u2 u– uCell uCycle
uData
Time u Interval Sets uof Number uof
uDNA
Phase Key uProcess (hours) present uin ueach ucell u organelles uin ueach
at uend uof uphase u u u u cell uat uend uof uphase
Gap1
Cell uGrowth 11 1 560
u
Synthesi
DNA uReplication 8 2 570
s
Protein uand
4 2 600
uorganelle usynthesis
Gap2
Mitosis Cell uand unuclear usplitting 1 1 300
Total utime: 24
8. Model u 2 u presents u cell u cycle u data u for u a u typical u human u cell u in u culture. u Use u the u phase
u names u in uModel u2 uto ulabel uthe uG, uM, uand uS uphases uin uModel u1.
9. Looking uat uthe uthird ucolumn uof uModel u2, ucompare uthe utime uspent uin umitosis uwith uthe
utime uspent uin ugap in uhuman ucells uand udescribe uany udifference.
1 u
Gap1 uis u11x ulonger uthan umitosis
2 POGIL™ u Activities u for u High u School u Biology
about:bla 2/6
nk
uPM uWorksheet
The Cell Cycle
u u
What ucontrols uthe ulife uand udevelopment uof ua
ucell?
Why?
An u old u piece u of u poetry usays u“to ueverything u there uis u a u season... u a u time u to ube u born, ua u time u to udie.”
u For u cells, uthe u line u might u say u “a u time u to u divide u and u a u time u to u grow.” u In u multicellular u organisms,
u different u types u of ucells uhave u different u roles u and uneed u to ucomplete u specific u tasks. u For uexample, u a
u cell uthat u isn’t u large u enough u is unot uuseful ufor ustoring unutrients ufor ulater, ubut ua ucell uthat uis utoo
ularge uwill unot ube uuseful ufor utransportation uthrough u a u tiny u capillary. u In u this u activity, u you u will
u learn u about u the u seasons u of u a u cell’s u life, u and u in u turn u better uunderstand uhow uorganisms ufunction.
Model u1 u– uThe uCell uCycle
G1
*
M Enters
(including ucytokinesis) uG0
G2
S
1. How u many u phases u are u in u the ucell u cycle u as u shown u in u the u diagram u in uModel u1?
4
2. Starting uat uthe ustarred ucell, uwhat uis uthe uorder uof uthe ustages uof ua ucell’s ulife?
G1,S,G2,M
3. During uwhich uphase udoes uthe usize uof uthe u cell u increase?
G1
4. During u which u phase u does u the u number u of u cells u increase?
M
The uCell uCycle 1
about:bla 1/6
nk
, 3/17/24, u10:19 POGIL u- uThe uCell uCycle
uPM uWorksheet
5. Considering uyour uanswer uto uQuestions u3 uand u4, uidentify utwo uways uthat uthe ugrowth uof uan
uorgan- uism ucan ube uaccomplished uthrough uthe uevents uof uthe ucell ucycle.
The ucells ucan ucontinue umultiplying u"endlessly", uresulting uin uthe ugrowth uof uthe uorganism uand
uthe ucells ucould ualso ugrow ufrom uG1.
6. Cancer, uthe uuncontrolled ugrowth uof ucells, uoften uresults uin ua utumor, uor umass uof
uabnormal ucells. uSome u cancerous u tumors u consist u of u many u cells u that u are u much u smaller
u than u normal. u According u to uModel u1, uwhat upart(s) uof uthe ucell ucycle uis u(are) umost ulikely
ubeing uaffected?
G1
7. In uModel u1, uif uthe ulength uof uthe uarrow urepresents utime, uthen ufor uthose ucancerous ucells,
uwhat uhap- upens uto uthe utime uthat uis unecessary ufor uthe ucell ucycle? uWhat uimplication umight
uthis uhave ufor udoctors uwho uare utreating ucancer upatients?
G1 uis uwhere uthe ucell uwill uspend uthe umost uamount u of utime.
Model u2 u– uCell uCycle
uData
Time u Interval Sets uof Number uof
uDNA
Phase Key uProcess (hours) present uin ueach ucell u organelles uin ueach
at uend uof uphase u u u u cell uat uend uof uphase
Gap1
Cell uGrowth 11 1 560
u
Synthesi
DNA uReplication 8 2 570
s
Protein uand
4 2 600
uorganelle usynthesis
Gap2
Mitosis Cell uand unuclear usplitting 1 1 300
Total utime: 24
8. Model u 2 u presents u cell u cycle u data u for u a u typical u human u cell u in u culture. u Use u the u phase
u names u in uModel u2 uto ulabel uthe uG, uM, uand uS uphases uin uModel u1.
9. Looking uat uthe uthird ucolumn uof uModel u2, ucompare uthe utime uspent uin umitosis uwith uthe
utime uspent uin ugap in uhuman ucells uand udescribe uany udifference.
1 u
Gap1 uis u11x ulonger uthan umitosis
2 POGIL™ u Activities u for u High u School u Biology
about:bla 2/6
nk
