NRP 511
Advanced Pathophysiology
FINAL EXAM REVIEW
©UOP 2024/2025
,1. Multiple Choice: Which of the following mechanisms is
primarily involved in the development of cardiogenic shock?
A. Systemic inflammatory response
B. Impaired myocardial contractility
C. Reduced renal perfusion
D. Hypermetabolic state
Correct Answer: B. Impaired myocardial contractility
Rationale: Cardiogenic shock is characterized by the heart's
inability to pump blood effectively, which is most commonly due to
impaired myocardial contractility.
2. Fill-in-the-Blank: The primary pathophysiological process of
asthma is ___________.
Correct Answer: Bronchoconstriction
Rationale: Asthma is characterized by bronchoconstriction, which
leads to reduced airflow and difficulty breathing.
3. True/False: Pulmonary edema is always a result of left-sided
heart failure.
Correct Answer: False
©UOP 2024/2025
, Rationale: While left-sided heart failure is a common cause of
pulmonary edema, it can also result from non-cardiac factors such
as acute respiratory distress syndrome (ARDS).
4. Multiple Response: Select all that apply. Which of the following
are recognized triggers for sickle cell crisis?
A. Dehydration
B. High altitude
C. Physical exertion
D. Hypothermia
Correct Answers: A, B, C, D
Rationale: All listed options are potential triggers for sickle cell
crisis, which can lead to vaso-occlusive events.
5. Multiple Choice: In type 1 diabetes mellitus, the destruction of
beta cells is primarily due to:
A. Autoimmune attack
B. Amyloid deposition
C. Genetic mutations
D. Insulin resistance
Correct Answer: A. Autoimmune attack
©UOP 2024/2025
Advanced Pathophysiology
FINAL EXAM REVIEW
©UOP 2024/2025
,1. Multiple Choice: Which of the following mechanisms is
primarily involved in the development of cardiogenic shock?
A. Systemic inflammatory response
B. Impaired myocardial contractility
C. Reduced renal perfusion
D. Hypermetabolic state
Correct Answer: B. Impaired myocardial contractility
Rationale: Cardiogenic shock is characterized by the heart's
inability to pump blood effectively, which is most commonly due to
impaired myocardial contractility.
2. Fill-in-the-Blank: The primary pathophysiological process of
asthma is ___________.
Correct Answer: Bronchoconstriction
Rationale: Asthma is characterized by bronchoconstriction, which
leads to reduced airflow and difficulty breathing.
3. True/False: Pulmonary edema is always a result of left-sided
heart failure.
Correct Answer: False
©UOP 2024/2025
, Rationale: While left-sided heart failure is a common cause of
pulmonary edema, it can also result from non-cardiac factors such
as acute respiratory distress syndrome (ARDS).
4. Multiple Response: Select all that apply. Which of the following
are recognized triggers for sickle cell crisis?
A. Dehydration
B. High altitude
C. Physical exertion
D. Hypothermia
Correct Answers: A, B, C, D
Rationale: All listed options are potential triggers for sickle cell
crisis, which can lead to vaso-occlusive events.
5. Multiple Choice: In type 1 diabetes mellitus, the destruction of
beta cells is primarily due to:
A. Autoimmune attack
B. Amyloid deposition
C. Genetic mutations
D. Insulin resistance
Correct Answer: A. Autoimmune attack
©UOP 2024/2025
