Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan

PROGRAMME GRANTS FOR APPLIED RESEARCH VOLUME 6 ISSUE 2 JUNE 2018 ISSN Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan Declan Murphy, Karen Glaser, Hannah Hayward, Hanna Eklund, Tim Cadman, James Findon, Emma Woodhouse, Karen Ashwood, Jennifer Beecham, Patrick Bolton, Fiona McEwen, Ellie Wilson, Christine Ecker, Ian Wong, Emily Simonoff, Ailsa Russell, Jane McCarthy, Eddie Chaplin, Susan Young and Philip Asherson DOI 10.3310/pgfar06020 Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan Declan Murphy,1* Karen Glaser,2 Hannah Hayward,1 Hanna Eklund,1 Tim Cadman,1 James Findon,1 Emma Woodhouse,3 Karen Ashwood,3 Jennifer Beecham,4 Patrick Bolton,5 Fiona McEwen,3,5 Ellie Wilson,1 Christine Ecker,1 Ian Wong,6 Emily Simonoff,5 Ailsa Russell,7 Jane McCarthy,8 Eddie Chaplin,1 Susan Young1 and Philip Asherson3 1Sackler Institute for Translational Neurodevelopment and Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King’s College London, London, UK 2Institute of Gerontology, King’s College London, London, UK 3Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London, UK 4London School of Economics and Political Science, London, UK 5Department of Child and Adolescent Psychiatry, Institute of Psychiatry, King’s College London, London, UK 6Department of Pharmacology and Pharmacy, University of Hong Kong, PokFuLam, Hong Kong 7Department of Psychology, University of Bath, Bath, UK 8St Andrew’s Healthcare, Northampton, UK *Corresponding author Declared competing interests of authors: Declan Murphy has received research funding from Shire (Basingstoke, UK) and leads the European Union (EU) Innovative Medicines Inititative consortium EU Autism Interventions– a Multicentre Study for Developing New Medications that receives funding from both the EU and the European Federation of Pharmaceutical Industries and Associations. Ian Wong received a research grant from the European Commission, Hong Kong Research Grant Council and Janssen-Cilag Ltd (High Wycombe, UK) on research to investigate the safety of antipsychotic drugs and attention deficit hyperactivity disorder treatments. In addition, Ailsa Russell has a patent Authors Copyright– Treatment Manual Cognitive–Behavioural Therapy for Obsessive–Compulsive Disorder in Autism Spectrum Disorder pending. Susan Young has received honoraria for consultancy, travel, educational talks and/or research from the Cognitive Centre of Canada, Janssen Pharmaceutical (Raritan, NJ, USA), Eli Lilly (Indianapolis, IN, USA), Novartis (Frimley, UK), HB Pharma (Sorø, Denmark), Flynn Pharma (Stevenage, UK) and Shire. Philip Asherson has received honoraria for consultancy, travel, educational talks and/or research from Janssen Pharmaceutical, Eli Lilly, Novartis, HB Pharma, Flynn Pharma and Shire. Published June 2018 DOI: 10.3310/pgfar06020 This report should be referenced as follows: Murphy D, Glaser K, Hayward H, Eklund H, Cadman T, Findon J, et al. Crossing the divide: a longitudinal study of effective treatments for people with autism and attention deficit hyperactivity disorder across the lifespan. Programme Grants Appl Res 2018;6(2). Programme Grants for Applied Research ISSN (Print) ISSN (Online) This journal is a member of and subscribes to the principles of the Committee on Publication Ethics (COPE) ( Editorial contact: The full PGfAR archive is freely available to view online at from the report pages of the NIHR Journals Library website: Criteria for inclusion in the Programme Grants for Applied Research journal Reports are published in Programme Grants for Applied Research (PGfAR) if (1) they have resulted from work for the PGfAR programme, and (2) they are of a sufficiently high scientific quality as assessed by the reviewers and editors. 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