Pharmacotherapeutics for Advanced
Practice Nurse Prescribers
Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT:
1) Reducing the dosage of one of the drugs
2) Scheduling their administration at different times
3) Prescribing a third drug to counteract the adverse reaction of the combination
4) Reducing the dosage of both drugs - ANSWER Prescribing a third drug to counteract the
adverse reaction of the combination
An example of a first-dose reaction that may occur includes:
1. Orthostatic hypotension that does not occur with repeated doses
2. Purple glove syndrome with phenytoin use
3. Hemolytic anemia from ceftriaxone use
4. Contact dermatitis from neomycin use - ANSWER Orthostatic hypotension that does not
occur with repeated doses
Are drugs that are disgnedated Schedule II by the DEA refillable - ANSWER No. A new
prescription needs to be written
Are there known drug reactions with Beclomethasone (QVAR) - ANSWER No
Azithromycin doing requires that the first day's doing be twice those of the other four day; This is
considered a loading does. What is a loading dose? - ANSWER Rapidly actives drug levels in
the therapeutic range
Based on the patients below, who is at high risk for experiencing an adverse drug reaction?
1) 32-year old male
2) 22- year told female
3) 3 month old female
4)48 year old male - ANSWER 3 month old
Cost-effectiveness analysis compares two or more treatments or programs that are: -
ANSWER not necessarily therapeutically equivalent
, Pharmacotherapeutics for Advanced
Practice Nurse Prescribers
Digoxin levels need to be monitored closely when the following medication is started:
1. Loratadine
2. Diphenhydramine
3. Ipratropium
4. Albuterol - ANSWER Albuterol
Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen - ANSWER Its narrow therapeutic index
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - ANSWER Are easily absorbed if they are
nonionized
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
4. Leads to a decreased physiological response when combined with another drug -
ANSWER Is modified by the concurrent administration of another drug
Drugs that are prone to cause adverse drug reactions include - ANSWER Insulins
Practice Nurse Prescribers
Actions taken to reduce drug—drug interaction problems include all of the following EXCEPT:
1) Reducing the dosage of one of the drugs
2) Scheduling their administration at different times
3) Prescribing a third drug to counteract the adverse reaction of the combination
4) Reducing the dosage of both drugs - ANSWER Prescribing a third drug to counteract the
adverse reaction of the combination
An example of a first-dose reaction that may occur includes:
1. Orthostatic hypotension that does not occur with repeated doses
2. Purple glove syndrome with phenytoin use
3. Hemolytic anemia from ceftriaxone use
4. Contact dermatitis from neomycin use - ANSWER Orthostatic hypotension that does not
occur with repeated doses
Are drugs that are disgnedated Schedule II by the DEA refillable - ANSWER No. A new
prescription needs to be written
Are there known drug reactions with Beclomethasone (QVAR) - ANSWER No
Azithromycin doing requires that the first day's doing be twice those of the other four day; This is
considered a loading does. What is a loading dose? - ANSWER Rapidly actives drug levels in
the therapeutic range
Based on the patients below, who is at high risk for experiencing an adverse drug reaction?
1) 32-year old male
2) 22- year told female
3) 3 month old female
4)48 year old male - ANSWER 3 month old
Cost-effectiveness analysis compares two or more treatments or programs that are: -
ANSWER not necessarily therapeutically equivalent
, Pharmacotherapeutics for Advanced
Practice Nurse Prescribers
Digoxin levels need to be monitored closely when the following medication is started:
1. Loratadine
2. Diphenhydramine
3. Ipratropium
4. Albuterol - ANSWER Albuterol
Digoxin may cause a type A adverse drug reaction due to:
1. Idiosyncratic effects
2. Its narrow therapeutic index
3. Being a teratogen
4. Being a carcinogen - ANSWER Its narrow therapeutic index
Drug administration via IV:
1) need to be lipid soluble in order to absorb easily
2) Begin distribution in the body immediately
3) Are easily absorbed if they are nonionized
4) May use pinocytosis to be absorbed - ANSWER Are easily absorbed if they are
nonionized
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
4. Leads to a decreased physiological response when combined with another drug -
ANSWER Is modified by the concurrent administration of another drug
Drugs that are prone to cause adverse drug reactions include - ANSWER Insulins
