CDCES Medications
What diabetes medications can contribute to weight loss? - ANSGLP-1, SGLT-2, Amylin Mimetic
What meds should be avoided in patients with CHF? - ANSActose/Avandia- TZD
Biguanides
What is the action? - ANSAction: Decreases hepatic glucose output
What are the names of Biguanide drugs? - ANSMetformin/ Glucophage
What are side effects of Biguanides? - ANSB12 deficiency, take with meals to avoid GI upset
**dont use if GFR <30, if already on metformin and GFR falls between 30-45, eval risk
Who is approved to use Biguanides? - ANSApproved in peds 10years + and adults
Sulfonylureas
Action - ANSStimulates sustained insulin release by pancreas
What are the names of the Sulfonylureas? - ANSGlyburide (Diabeta)
Glipizide (Glucotrol,. Glucotrol XL)
Glimepiride (Amaryl)
Side effects of Sulfonylureas? - ANSWeight Gain
Hypoglycemia
What is the duration of Sulfonlyureas? - ANS12-24hrs
SGLT2 inhibitors/ Glucoretics, What is the action? - ANSDecreases glucose reabsorption in the
kidney. It brings the threshold of the kidney back to 180mg/dl, so the kidney begins to excrete
excess glucose earlier (at 180 vs 220mg/dl)
What are the names of the SGLT2 inhibitors/ Glucoretics? - ANSCanagliflozin (Invokana)
Dapagliflozin (Farxiga)
Empagliflozin (Jardiance)
Ertugliflozin (Steglatro)
What are side effects of SGLT2 inhibitors/ Glucoretics? - ANSHypotension
UTI
What diabetes medications can contribute to weight loss? - ANSGLP-1, SGLT-2, Amylin Mimetic
What meds should be avoided in patients with CHF? - ANSActose/Avandia- TZD
Biguanides
What is the action? - ANSAction: Decreases hepatic glucose output
What are the names of Biguanide drugs? - ANSMetformin/ Glucophage
What are side effects of Biguanides? - ANSB12 deficiency, take with meals to avoid GI upset
**dont use if GFR <30, if already on metformin and GFR falls between 30-45, eval risk
Who is approved to use Biguanides? - ANSApproved in peds 10years + and adults
Sulfonylureas
Action - ANSStimulates sustained insulin release by pancreas
What are the names of the Sulfonylureas? - ANSGlyburide (Diabeta)
Glipizide (Glucotrol,. Glucotrol XL)
Glimepiride (Amaryl)
Side effects of Sulfonylureas? - ANSWeight Gain
Hypoglycemia
What is the duration of Sulfonlyureas? - ANS12-24hrs
SGLT2 inhibitors/ Glucoretics, What is the action? - ANSDecreases glucose reabsorption in the
kidney. It brings the threshold of the kidney back to 180mg/dl, so the kidney begins to excrete
excess glucose earlier (at 180 vs 220mg/dl)
What are the names of the SGLT2 inhibitors/ Glucoretics? - ANSCanagliflozin (Invokana)
Dapagliflozin (Farxiga)
Empagliflozin (Jardiance)
Ertugliflozin (Steglatro)
What are side effects of SGLT2 inhibitors/ Glucoretics? - ANSHypotension
UTI
