Pathophysiology MCQs
PATHOPHYSIOLOGY MCQS – ULTIMATE, ALL STAR AND
ELITE|QUESTIONS AND CORRECT ANSWERS 2025|100% PASS
I Made This Document For Pathophysiology, It Contains All New Mcqs, That
I’ve Received And I’ve Answered The Ones That Needed Answering. In Total
It Has Around 1000 New Mcqs From Colloquiums And Exams.
The Ones I Wasn’t More Then 90% Sure About, I’ve Said Check After My
Answer.
Pages 1-120 Contains All New Mcqs.
Pages 121-247 Contains All Old Mcqs From The Website, That Are All
Answered
2) Which is the most effective long-term adaptation which can be developed at high altitude
sojourn?
a. Hyperventilation
b. polycythemia
c. Increased pulmonary diffusion capacity
d. Increased affinity of the haemoglobin to oxygen
e. Tachycardia
3) Which of the following statements regarding the bleeding disorders is TRUE?
a. Low platelets count is expected in splenomegaly
b. Hemophilia A affects only women
c. Platelets are produced in the spleen
d. Hemophilia B affects only women
4) The receptors for pain are called:
a. Baroreceptors
b. Aloceptors
c. Nociceptors
d. Trauma receptors
e. velociraptors
5) Which of the following statements about pneumothorax is TRUE?
a. Tension pneumothorax could be successfully treated by injecting high dose of
corticosteroids
b. Tension pneumothorax describes a condition of excessive fluid collection in the lung
c. Pneumothorax causes partial or complete collapse of the affected lung
, d. Open pneumothorax occurs when a blood vessel on the lung surface ruptures.
6) How is the clinical sign of bulky, frothy, pale stool, caused by impaired lipid digestion
called?
a. Steatorrhea
b. cachexia
c. Logorrhea
d. Lipidorrhea
e. None of above
7) Which are the organs directly involved in the elimination of protons from the organism
regarding the maintenance of the acid base balance?
a. Liver and heart
b. Kidney and heart
c. Lungs and kidneys
d. Liver and kidneys
e. Heart and lungs
8) Which of the following statements regarding the functional manifestations of liver
cirrhosis is TRUE?
a. Patients with advanced liver cirrhosis are hypoglycemic due to increased glucose
consumption, resulting from decreased beta oxidation in the hepatocyte.
b. Patients with advanced liver cirrhosis are hyperglycemic due to damage to the
pancreas by the inflammatory process.
c. Patients with advanced liver cirrhosis are hyperglycemic, due to impaired glucose
metabolism in the liver.
d. Patients with advanced liver cirrhosis are predisposed to night time hypoglycemia
due to decreased glycogen storage.
9) Which of the following is the most common way of developing a pyelonephritis?
a. Ascending infection with gram (+) bacteria
b. Descending infection with gram (+) bacteria
c. Ascending infection with gram (-) bacteria
d. Descending infection with gram (-) bacteria
10) Which of the following statements regarding glomerulonephritis is TRUE?
a. Always presents with nephrotic syndrome
b. May present with nephritis or nephrotic syndrome, depending on the type of
glomerulonephritis
c. Nephritic or nephrotic syndrome will be present only in the terminal stages of
chronic kidney disease.
d. Always presents with nephritic syndrome
11) Which type of hypoxia is usually present in patients with liver cirrhosis?
a. Mixed hypoxia
b. Haemic hypoxia
c. No hypoxia is present
d. Hypoxic hypoxia
, e. Circulatory hypoxia
12) Which of following statements regarding respiratory acidosis is FALSE?
a. pCO2 in compensated respiratory acidosis is normal
b. Respiratory acidosis is compensated by metabolic alkalosis
c. HCO3 levels in non compensated respiratory acidosis are normal
d. pH in compensated respiratory acidosis is normal
13) Which of the following is NOT a mechanism for the development of endocrine
hyperfunction?
a. Increased hormonal production in the gland
b. Increased stimulation of the gland
c. Ecotopic production of a hormone
d. Receptor defects
14) Which of the following statements regarding the role of Aspirin in relation to the
coagulation cascade is TRUE?
a. increases the release of NO from the endothelium leading to endothelial leakage and
vasopathy.
b. Irreversibly blocks COX1 in platelets disturbing their function
c. Suppresses the thrombosis
d. Binds to antithrombin II (AT III) and leads to structural activation of the latter leading
to coagulopathy
15) What is the erythrocyte morphology in vitamin B12 deficiency anemia?
a. Hyperchromic and microcytic
b. Macrocytic and hyperchromic
c. Hyperchromic and normocytic
d. Hypochromic and microcytic
16) Which of the following statements regarding dyslipedemias is TRUE?
a. They have no negative impact on the organism
b. All of them are easily treated with diet
c. They are classified as primary and acquired
d. Affect only males, because they have X recessive inheritance
17) Impaired diffusion could result from all of the following conditions. EXCEPT
a. Decreased contact time between blood and the gas exchange area
b. Reduction of the alveolar capillary surface
c. Alveolar hyperventilation
d. Thickening of the alveolar capillary barrier
18) Which of the following statements is NOT true for the stable angina?
a. It is caused by increased myocardial demands for oxygen
b. It is cause by atherosclerosis of a coronary artery
c. It is relieved by rest
d. The pain appears during physical exercise
e. It is caused by coronary artery thrombosis
, 19) which of the following is NOT a factor for edema development?
a. Decreased osmotic pressure
b. Increased permeability
c. Decreased lymphatic drainage
d. Increased hydrostatic pressure
20) Which of the following could be a potential mechanism for the stimulation of cellular
proliferation caused by promoters, regarding the pathogenesis of cancer development?
a. Stimulating oncogenes in the genome of the cell
b. Increasing surface receptors for growth factors
c. Tumour suppressor gene to be deactivated
d. All answers are correct
21) Which of the following conditions could be a reason to develop hypercalcemia?
a. Liver failure
b. Multiple myeloma
c. Hypothyroidism
d. Pseudohypoparathyroidism
22) Which of the following pathogenetic mechanisms is responsible for the development of
anemia in liver cirrhosis?
a. Chronic hemorrhage
b. Fe and Vit B12 deficiency
c. Hypoplastic erythropoiesis
d. Extravascular hemolysis
e. All of the above
23) which of the following is TRUE for the cytotoxic type of hypersensitivity reactions?
a. There is proliferation of sensitized CD4+ T-lymphocyte
b. Antibodies are formed against antigens on body cells
c. They are IgE mediated
d. There is deposition of circulating antigen antibody complexes
24) Which of the following is NOT a characteristic of oligo anuric stage of acute kidney injury
(acute renal failure)?
a. Hypokaliemia and associated with it increased risk of fatal arrhythmias
b. Decrease in diuresis c400ml/24h with subsequent hypervolemia
c. Metabolic acidosis
d. Hypervolemia and increased risk for fatal pulmonary and cerebral edema
25) Which of the following is NOT a type of shock?
a. Obstructive
b. Restrictive
c. Cardiogenic
d. Hypovolemic
26) Which of the following conditions could be a potential cause for the development of
renovascular hypertension?
a. Glomerulonephritis
PATHOPHYSIOLOGY MCQS – ULTIMATE, ALL STAR AND
ELITE|QUESTIONS AND CORRECT ANSWERS 2025|100% PASS
I Made This Document For Pathophysiology, It Contains All New Mcqs, That
I’ve Received And I’ve Answered The Ones That Needed Answering. In Total
It Has Around 1000 New Mcqs From Colloquiums And Exams.
The Ones I Wasn’t More Then 90% Sure About, I’ve Said Check After My
Answer.
Pages 1-120 Contains All New Mcqs.
Pages 121-247 Contains All Old Mcqs From The Website, That Are All
Answered
2) Which is the most effective long-term adaptation which can be developed at high altitude
sojourn?
a. Hyperventilation
b. polycythemia
c. Increased pulmonary diffusion capacity
d. Increased affinity of the haemoglobin to oxygen
e. Tachycardia
3) Which of the following statements regarding the bleeding disorders is TRUE?
a. Low platelets count is expected in splenomegaly
b. Hemophilia A affects only women
c. Platelets are produced in the spleen
d. Hemophilia B affects only women
4) The receptors for pain are called:
a. Baroreceptors
b. Aloceptors
c. Nociceptors
d. Trauma receptors
e. velociraptors
5) Which of the following statements about pneumothorax is TRUE?
a. Tension pneumothorax could be successfully treated by injecting high dose of
corticosteroids
b. Tension pneumothorax describes a condition of excessive fluid collection in the lung
c. Pneumothorax causes partial or complete collapse of the affected lung
, d. Open pneumothorax occurs when a blood vessel on the lung surface ruptures.
6) How is the clinical sign of bulky, frothy, pale stool, caused by impaired lipid digestion
called?
a. Steatorrhea
b. cachexia
c. Logorrhea
d. Lipidorrhea
e. None of above
7) Which are the organs directly involved in the elimination of protons from the organism
regarding the maintenance of the acid base balance?
a. Liver and heart
b. Kidney and heart
c. Lungs and kidneys
d. Liver and kidneys
e. Heart and lungs
8) Which of the following statements regarding the functional manifestations of liver
cirrhosis is TRUE?
a. Patients with advanced liver cirrhosis are hypoglycemic due to increased glucose
consumption, resulting from decreased beta oxidation in the hepatocyte.
b. Patients with advanced liver cirrhosis are hyperglycemic due to damage to the
pancreas by the inflammatory process.
c. Patients with advanced liver cirrhosis are hyperglycemic, due to impaired glucose
metabolism in the liver.
d. Patients with advanced liver cirrhosis are predisposed to night time hypoglycemia
due to decreased glycogen storage.
9) Which of the following is the most common way of developing a pyelonephritis?
a. Ascending infection with gram (+) bacteria
b. Descending infection with gram (+) bacteria
c. Ascending infection with gram (-) bacteria
d. Descending infection with gram (-) bacteria
10) Which of the following statements regarding glomerulonephritis is TRUE?
a. Always presents with nephrotic syndrome
b. May present with nephritis or nephrotic syndrome, depending on the type of
glomerulonephritis
c. Nephritic or nephrotic syndrome will be present only in the terminal stages of
chronic kidney disease.
d. Always presents with nephritic syndrome
11) Which type of hypoxia is usually present in patients with liver cirrhosis?
a. Mixed hypoxia
b. Haemic hypoxia
c. No hypoxia is present
d. Hypoxic hypoxia
, e. Circulatory hypoxia
12) Which of following statements regarding respiratory acidosis is FALSE?
a. pCO2 in compensated respiratory acidosis is normal
b. Respiratory acidosis is compensated by metabolic alkalosis
c. HCO3 levels in non compensated respiratory acidosis are normal
d. pH in compensated respiratory acidosis is normal
13) Which of the following is NOT a mechanism for the development of endocrine
hyperfunction?
a. Increased hormonal production in the gland
b. Increased stimulation of the gland
c. Ecotopic production of a hormone
d. Receptor defects
14) Which of the following statements regarding the role of Aspirin in relation to the
coagulation cascade is TRUE?
a. increases the release of NO from the endothelium leading to endothelial leakage and
vasopathy.
b. Irreversibly blocks COX1 in platelets disturbing their function
c. Suppresses the thrombosis
d. Binds to antithrombin II (AT III) and leads to structural activation of the latter leading
to coagulopathy
15) What is the erythrocyte morphology in vitamin B12 deficiency anemia?
a. Hyperchromic and microcytic
b. Macrocytic and hyperchromic
c. Hyperchromic and normocytic
d. Hypochromic and microcytic
16) Which of the following statements regarding dyslipedemias is TRUE?
a. They have no negative impact on the organism
b. All of them are easily treated with diet
c. They are classified as primary and acquired
d. Affect only males, because they have X recessive inheritance
17) Impaired diffusion could result from all of the following conditions. EXCEPT
a. Decreased contact time between blood and the gas exchange area
b. Reduction of the alveolar capillary surface
c. Alveolar hyperventilation
d. Thickening of the alveolar capillary barrier
18) Which of the following statements is NOT true for the stable angina?
a. It is caused by increased myocardial demands for oxygen
b. It is cause by atherosclerosis of a coronary artery
c. It is relieved by rest
d. The pain appears during physical exercise
e. It is caused by coronary artery thrombosis
, 19) which of the following is NOT a factor for edema development?
a. Decreased osmotic pressure
b. Increased permeability
c. Decreased lymphatic drainage
d. Increased hydrostatic pressure
20) Which of the following could be a potential mechanism for the stimulation of cellular
proliferation caused by promoters, regarding the pathogenesis of cancer development?
a. Stimulating oncogenes in the genome of the cell
b. Increasing surface receptors for growth factors
c. Tumour suppressor gene to be deactivated
d. All answers are correct
21) Which of the following conditions could be a reason to develop hypercalcemia?
a. Liver failure
b. Multiple myeloma
c. Hypothyroidism
d. Pseudohypoparathyroidism
22) Which of the following pathogenetic mechanisms is responsible for the development of
anemia in liver cirrhosis?
a. Chronic hemorrhage
b. Fe and Vit B12 deficiency
c. Hypoplastic erythropoiesis
d. Extravascular hemolysis
e. All of the above
23) which of the following is TRUE for the cytotoxic type of hypersensitivity reactions?
a. There is proliferation of sensitized CD4+ T-lymphocyte
b. Antibodies are formed against antigens on body cells
c. They are IgE mediated
d. There is deposition of circulating antigen antibody complexes
24) Which of the following is NOT a characteristic of oligo anuric stage of acute kidney injury
(acute renal failure)?
a. Hypokaliemia and associated with it increased risk of fatal arrhythmias
b. Decrease in diuresis c400ml/24h with subsequent hypervolemia
c. Metabolic acidosis
d. Hypervolemia and increased risk for fatal pulmonary and cerebral edema
25) Which of the following is NOT a type of shock?
a. Obstructive
b. Restrictive
c. Cardiogenic
d. Hypovolemic
26) Which of the following conditions could be a potential cause for the development of
renovascular hypertension?
a. Glomerulonephritis
