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COMSAE Cramming Exam Questions and Complete Solutions Graded A+.

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COMSAE Cramming Exam Questions and Complete Solutions Graded A+.

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Comsae 110
Course
Comsae 110











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Institution
Comsae 110
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Comsae 110

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August 21, 2024
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Written in
2024/2025
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COMSAE
Cramming Exam
Questions and
Complete Solutions
Graded A+
Denning [Date] [Course title]

,drug for UC/Crohns - Answer: sulfasalazine



pulmonary effects of CF - Answer: chronic bronchitis and bronchiectasis



osteoporosis affects what parts of bone? - Answer: (spongy and ) trabecular bone mass loss



Imipramine is what type of drug? - Answer: TCA



SE: Tri-Cs

convulsions

coma

cardiotox



antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block alpha1)



loratidine vs ranitidine - Answer: loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less sedating



ranitidine: H2 receptor antagonist (like cimetidine)



H1 think allergies

H2 think gastric



What organism presents as cells w RBCs inside - Answer: entaemoba histolytica



which type of pneumothorax causes tracheal deviation to the contra side? - Answer: tension



intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels -
Answer: AVM arteriovenous malformation

,What is a cavernous hemangioma - Answer: benign tumor of liver, A/W VHL



anti-HepB surface antibody is only present in what population - Answer: recovered or immunized



not in chronic or acute



proctalgia fugax is a form of what? - Answer: levator ani syndrome



Proctalgia fugax is a form of levator syndrome (also called levator ani syndrome). Both include spasms of
muscles in the pelvic area. Proctalgia fugax is temporary, but other types of levator syndrome can last
for several days. Another major difference is the location of the pain.



fasciculus is UMN or LMN lesion? - Answer: LMN



antibodies in hashimotos attacks - Answer: thyroid peroxidase or antithyroglobulin



enlarged non tender thyroid



2 factors that influence starling curve - Answer: x axis- preload (EDV)

y axis- stroke volume or CO



treatment for fibromyalgia includes - Answer: TCA, SNRIs anticonvulsants



what drugs block NE reuptake? - Answer: TCA or SNRIs



possible complication of pagets bone disease - Answer: osteocarcoma



what does Hct tell you? - Answer: ratio of volume of RBCs compared to total blood volume

, Probenecid MOA ? Common risk factor? - Answer: inhibits reabsoprtion of uric acid in PCT

- also inhibits secretion of PCN

- can cause uric acid calculi



2 causes of SCID include - Answer: 1.) ADA deficiency

(adenosine deaminase required for degradation of adenosim and deoxyadenosine

- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID



2.) (most common) mutations in the gamma chain shared by a number of interleukin receptors (X-SCID)



lithiums effects on urination - Answer: inhibits vasopression/ADH --> increased urinary frequency —>
diabetes insipidus



infertility drug that can result in multiple fetuses? MOA? Side effects? - Answer: clomiphene (clones-
multiple babies)



antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)



upregulates LH and FSH release from pituitary --> ovulation



Used to treat infertility and polycystic ovarian syndrome. may cause hot flashes, ovarian enlargement,
multiple simultaneous pregnancies and visual disturbances.



AFP levels in down syndrome? - Answer: low AFP



Which GI malformation is A/W down syndrome - Answer: Hirschprungs- congenital aganglionic
megacolon



defective relaxation and peristalsis of rectum and distal sigmoid colon

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