ONS/ONCC Chemotherapy Immunotherapy
Certificate Exam Latest 2024-2025 actual
exam Questions And Answers (Verified
Answers)
What is unique about nitrosoureas agents? Correct Answer Able
to cross the blood-brain barrier; can be effective in treating some
brain tumors
2 types of therapies that commonly have cutaneous reactions:
Correct Answer 1. EGFR inhibitor therapies
2. Antimetabolites
Common nitrosoureas agents: Correct Answer Carmustine
(BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: Correct Answer
Carboplatin
These agents are typically categorized as highly emetogenic:
Correct Answer 1. Alkylating agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas:
Correct Answer BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? Correct Answer Bladder
protectant with administration of cyclophosphamide or ifosfamide
,Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment Correct
Answer Oxaliplatin
How do antimetabolites function? Correct Answer By blocking
DNA and RNA growth by interfering with enzymes needed for
normal cell metabolism
Antimetabolites work in the ___ phase. Correct Answer S
Common side effects of antimetabolites: Correct Answer
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: Correct Answer Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what
route of administration for vincristine? Correct Answer IV
piggyback via gravity
Anthracycline antitumor abx work by: Correct Answer Interfering
with enzymes necessary for DNA to replicate in ALL phases of
the cell cycle
The two major classifications of antitumor antibiotics are: Correct
Answer Anthracyclines
Non-anthracyclines
, Common anthracycline antitumor abx: Correct Answer
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has
anthracycline-type properties. Correct Answer Mitoxantrone
Common non-anthracycline antitumor abx: Correct Answer
Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: Correct Answer Vesicant -
-> extravasation
Cardiac function
Lifetime dose tracking (cardiotoxicity)
Lifetime dose of doxorubicin should not exceed: Correct Answer
550 mg/m^2
What cardiac protectant medication can be administered prior to
doxorubicin? Correct Answer Dexrazoxane
Significant side effects of doxorubicin are: Correct Answer
Cardiotoxicity
N/V
Mucositis
Diarrhea
Severe myelosuppression
Hepatic impairment
Secondary cancers
Certificate Exam Latest 2024-2025 actual
exam Questions And Answers (Verified
Answers)
What is unique about nitrosoureas agents? Correct Answer Able
to cross the blood-brain barrier; can be effective in treating some
brain tumors
2 types of therapies that commonly have cutaneous reactions:
Correct Answer 1. EGFR inhibitor therapies
2. Antimetabolites
Common nitrosoureas agents: Correct Answer Carmustine
(BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: Correct Answer
Carboplatin
These agents are typically categorized as highly emetogenic:
Correct Answer 1. Alkylating agents
2. Nitrosoureas
Pre-administration labs for alkylating agents and nitrosoureas:
Correct Answer BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? Correct Answer Bladder
protectant with administration of cyclophosphamide or ifosfamide
,Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment Correct
Answer Oxaliplatin
How do antimetabolites function? Correct Answer By blocking
DNA and RNA growth by interfering with enzymes needed for
normal cell metabolism
Antimetabolites work in the ___ phase. Correct Answer S
Common side effects of antimetabolites: Correct Answer
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: Correct Answer Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what
route of administration for vincristine? Correct Answer IV
piggyback via gravity
Anthracycline antitumor abx work by: Correct Answer Interfering
with enzymes necessary for DNA to replicate in ALL phases of
the cell cycle
The two major classifications of antitumor antibiotics are: Correct
Answer Anthracyclines
Non-anthracyclines
, Common anthracycline antitumor abx: Correct Answer
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has
anthracycline-type properties. Correct Answer Mitoxantrone
Common non-anthracycline antitumor abx: Correct Answer
Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: Correct Answer Vesicant -
-> extravasation
Cardiac function
Lifetime dose tracking (cardiotoxicity)
Lifetime dose of doxorubicin should not exceed: Correct Answer
550 mg/m^2
What cardiac protectant medication can be administered prior to
doxorubicin? Correct Answer Dexrazoxane
Significant side effects of doxorubicin are: Correct Answer
Cardiotoxicity
N/V
Mucositis
Diarrhea
Severe myelosuppression
Hepatic impairment
Secondary cancers
