CORRECT ANSWER
naloxone - ANSWER MOA: Pure opioid antagonist that competes and displaces
opioids at opioid receptor sites.
methadone, buprenorphine, buprenorphine+naloxone - ANSWER Treatments for
opioid use disorder.
buprenorphine+naloxone - ANSWER Treatment for opioid use disorder with
comorbid pain.
opioids - ANSWER Inappropriate use of what substance may be due to uncontrolled
pain?
tablet, injectable, implant - ANSWER Naltrexone delivery methods.
implant - ANSWER Form of naltrexone limited to inpatient use.
buprenorphine - ANSWER Mu receptor partial agonist for opioid withdrawal.
buprenorphine - ANSWER Taking this medication too soon after last opioid use
increases the chances of intense withdrawal that comes on very quickly (precipitated
withdrawal).
opioid intoxication - ANSWER Symptoms include nausea and vomiting, respiratory
depression, constipation, itching, mioisis (small pupil). Patient will experience
euphoria and sedation.
opioid withdrawal - ANSWER Symptoms include N/V/D and dehydration, irritability,
restlessness, yawning, and twitching, increased HR/BP, chills, increased
temperature, rhinorrhea, lacrimation, dilated pupils.
naloxone - ANSWER Treatment for opioid intoxication during which cardiac or
respiratory depression is a concern.
cocaine intoxication - ANSWER Symptoms include dilated pupils, HA, tremor, hyper-
reflexia, twitching, seizures, or coma, increased HR/BP, arrhythmias, and MI, N/V,
incontinence/ARF, or rhabdomyolysis
cocaine intoxication - ANSWER Treatment includes BZD, antipsychotics, and
management of medical problems including HTN, stroke, cardiac arrhythmias,
hyperthermia, and seizures.
cocaine - ANSWER The use of beta blockers for treatment of chest pain and MI
during this intoxication is to be avoided due to unopposed a adrenergic stimulation.
, alcohol intoxication - ANSWER Signs vary with blood levels, from decreased
reaction time, muscle incoordination, ataxia, dysarthria, to respiratory failure and
coma.
severe alcohol intoxication - ANSWER Treatment includes cardiopulmonary function
maintenance, thiamine, and haloperidol PRN agitation.
thiamine - ANSWER Given IM/IV for 3 days to prevent Wernicke's encephalopathy,
along with IV fluids and a banana bag.
benzodiazepines - ANSWER Class of drugs to avoid for acute alcohol intoxication.
uncomplicated alcohol withdrawal - ANSWER Treatment includes BZD in either
symptom triggered or fixed dose; diazepam and chlordiazepoxide have a longer half
life, and oxazepam and lorazepam are suitable for patients with hepatic dysfunction.
diazepam and chlordiazepoxide - ANSWER BZDs with a long half-life used to treat
AUD.
oxazepam and lorazepam - ANSWER BZDs with moderate half-life used in AUD
patients with liver disease.
alcohol withdrawal seizures - ANSWER Treatment includes diazepam IV or
lorazepam IV/IM, thiamine IV/IM, and addressing electrolyte imbalances.
DT - ANSWER Treatment includes acute care management, parenteral diazepam or
lorazepam, thiamine, and antipsychotics if necessary.
disulfiram - ANSWER MOA is via negative reinforcement, where drinking is avoided
due to unpleasant effects.
acamprosate - ANSWER NMDA receptor antagonist that is renally cleared, suitable
for AUD patients with hepatic dysfunction.
naltrexone - ANSWER Treatment suitable for AUD with comorbid OUD, reducing
consumption by decreasing reinforcing properties.
NRT - ANSWER Only deals with physical dependence, does not address the
psychological component of smoking.
varenicline, bupropion, clonidine - ANSWER Oral stop-smoking aids, remember
*Very Bad Cancer*
buproprion - ANSWER Patients on what medication for smoking cessation treatment
should be observed for neuropsychiatric symptoms including changes in behavior,
hostility, agitation, depressed mood, and suicide-related events, including ideation,
behavior, and attempted suicide.
IV BZD - ANSWER How would you treat cocaine induced chest pain/myocardial
infarction?