Pharmacology Exam #3 review
questions
1. What is the mechanism of action for dabigatran etexilate?
a. In active form, has been shown to specifically and reversibly inhibit both free and
fibrin-bound thrombin, thereby inhibiting coagulation.
b. Acts on the liver to prevent synthesis of vitamin K-dependent clotting factors (II, VII,
IX, and X).
c. Combines with antithrombin II to inactivate clotting factors IX, X, XI and XIIinhibits the
conversion of prothrombin to thrombinprevents thrombus from forming.
d. Inhibits factor Xa->inhibits platelet aggregation and formation of fibrin clotting.correct
answers A.
A 36-year-old has been taking atorvastatin 20 mg PO daily for 6 months to treat mild
dyslipidemia. At a clinic appointment, she tells the nurse she is 6-weeks pregnant. The
nurse counsels the patient that it is likely the midwife will advise which of the following:
A. To increase the dose of prenatal vitamins
B. To reduce the dosage of her lovastatin to 20 mg PO daily
C. To increase the dosage to 40mg PO twice daily
D. About discontinuing the drug during pregnancycorrect answers D. About
discontinuing the drug during pregnancy
John Jones, a 47-year-old teacher, now takes cholestyramine, and the nurse teaches
him about the medication and its use. The nurse should be concerned if, after the
teaching session, Mr. Johns states:
A."I should take the medication with a full glass of water when I take my other
medications"
B."I am taking this medication to decrease my LDL cholesterol level"
C."I should swallow the tables whole"
D."I may need to supplement my intake of the fat-soluble vitamins A, D, e, and K"correct
answers A. and C. (getting correct answer from Prof. Monforte today!)
A person with type 1 diabetes mellitus and hypertension has the following lipid profile:
total serum cholesterol 288 mg/dL, low-density lipoprotein (LDL) cholesterol 200 mg/dL,
high-density lipoprotein (HDL) cholesterol 48 mg/dL, and triglycerides 200 mg/dL. How
would you evaluate the results of the lipid profile? (Select all that apply.)
A. LDL cholesterol is elevated.
B. HDL cholesterol is within normal limits.
C. Triglyceride level is elevated.
D. Total cholesterol is within normal limits.correct answers A.,B., and C
, What is the antidote for Anteplase (tPA)?correct answers Aminocaproic acid
Match the Antidote to the Medication!
Antidote:
___ Vitamin K
___ Narcan
___ Protamine Sulfate
__ Andexxa
___ Flumazenil
___ Acetylcysteine
Medication:
A.Heparin
B.Warfarin
C.Lorazepam
D.Rivaroxaban (Xarelto)
E.Morphine
F.Acetaminophencorrect answers B, E, A, D,C,F
Mrs. Heart's Vital signs:
▪VS:
▪Temp-37
▪BP-100/60
▪HR 170
▪SpO2 92%
▪RR-22
▪Which medication would you think the patient would be started on?
A)Lidocaine
B)Flecainide
C) Amiodarone
D)Diltiazemcorrect answers D)Diltiazem
Mrs. Heart's Vital signs:
▪VS:
▪Temp-37
▪BP-100/60
▪HR 170
▪SpO2 92%
▪RR-22
§What is a very concerning side affect of someone in atrial-fibrillation?
A)Pulmonary edema
B)Blood clots
C)Change in mental status
D)Loss of hearingcorrect answers B)Blood clots
▪Which anticoagulant, do you think Mrs. Heart will be started on in the hospital?
A) Heparin
questions
1. What is the mechanism of action for dabigatran etexilate?
a. In active form, has been shown to specifically and reversibly inhibit both free and
fibrin-bound thrombin, thereby inhibiting coagulation.
b. Acts on the liver to prevent synthesis of vitamin K-dependent clotting factors (II, VII,
IX, and X).
c. Combines with antithrombin II to inactivate clotting factors IX, X, XI and XIIinhibits the
conversion of prothrombin to thrombinprevents thrombus from forming.
d. Inhibits factor Xa->inhibits platelet aggregation and formation of fibrin clotting.correct
answers A.
A 36-year-old has been taking atorvastatin 20 mg PO daily for 6 months to treat mild
dyslipidemia. At a clinic appointment, she tells the nurse she is 6-weeks pregnant. The
nurse counsels the patient that it is likely the midwife will advise which of the following:
A. To increase the dose of prenatal vitamins
B. To reduce the dosage of her lovastatin to 20 mg PO daily
C. To increase the dosage to 40mg PO twice daily
D. About discontinuing the drug during pregnancycorrect answers D. About
discontinuing the drug during pregnancy
John Jones, a 47-year-old teacher, now takes cholestyramine, and the nurse teaches
him about the medication and its use. The nurse should be concerned if, after the
teaching session, Mr. Johns states:
A."I should take the medication with a full glass of water when I take my other
medications"
B."I am taking this medication to decrease my LDL cholesterol level"
C."I should swallow the tables whole"
D."I may need to supplement my intake of the fat-soluble vitamins A, D, e, and K"correct
answers A. and C. (getting correct answer from Prof. Monforte today!)
A person with type 1 diabetes mellitus and hypertension has the following lipid profile:
total serum cholesterol 288 mg/dL, low-density lipoprotein (LDL) cholesterol 200 mg/dL,
high-density lipoprotein (HDL) cholesterol 48 mg/dL, and triglycerides 200 mg/dL. How
would you evaluate the results of the lipid profile? (Select all that apply.)
A. LDL cholesterol is elevated.
B. HDL cholesterol is within normal limits.
C. Triglyceride level is elevated.
D. Total cholesterol is within normal limits.correct answers A.,B., and C
, What is the antidote for Anteplase (tPA)?correct answers Aminocaproic acid
Match the Antidote to the Medication!
Antidote:
___ Vitamin K
___ Narcan
___ Protamine Sulfate
__ Andexxa
___ Flumazenil
___ Acetylcysteine
Medication:
A.Heparin
B.Warfarin
C.Lorazepam
D.Rivaroxaban (Xarelto)
E.Morphine
F.Acetaminophencorrect answers B, E, A, D,C,F
Mrs. Heart's Vital signs:
▪VS:
▪Temp-37
▪BP-100/60
▪HR 170
▪SpO2 92%
▪RR-22
▪Which medication would you think the patient would be started on?
A)Lidocaine
B)Flecainide
C) Amiodarone
D)Diltiazemcorrect answers D)Diltiazem
Mrs. Heart's Vital signs:
▪VS:
▪Temp-37
▪BP-100/60
▪HR 170
▪SpO2 92%
▪RR-22
§What is a very concerning side affect of someone in atrial-fibrillation?
A)Pulmonary edema
B)Blood clots
C)Change in mental status
D)Loss of hearingcorrect answers B)Blood clots
▪Which anticoagulant, do you think Mrs. Heart will be started on in the hospital?
A) Heparin
