Adams Chapter 4
The nurse is conducting medication education for patients with hypertension. The focus
of the education is on enhancing the absorption of their medications. The nurse
determines that learning has occurred when the patients make which statement?
1. We can safely take the drug for at least 6 months beyond the expiration date.
2. We dont need to worry about storage of the drug, it wont lose potency.
3. We should not take our medications with milk or dairy products.
4. We need to be careful about taking the medication with certain foods. correct
answers Correct Answer: 4
Rationale 1: Food can alter the absorption of many medications. Storage can affect the
medications strength and may affect how it responds in the body. There are many more
foods that will alter the absorption of medications other than milk and dairy products.
Patients should be taught to avoid taking medications beyond the expiration date.
The physician ordered a loading dose of medication for the patient; it is to be followed
by a lower dose. When the patient receives the lower dose, she says to the nurse, I
think my doctor made a mistake; my medication dose is too low. What is the best
response by the nurse?
1. The initial dose shortened the half-life, so the medication would work more quickly.
2. We always give medications this way; the doctor did not make a mistake.
3. You had a larger dose initially so that the medication would work more quickly.
4. Giving a larger dose initially will reduce the chance of side effects. correct answers
Correct Answer: 3
Rationale 1: Loading doses of medications are used to quickly induce a therapeutic
response. Loading doses do not shorten the half-life of a drug. Not all medications are
initiated with a loading dose. Loading doses do not reduce the occurrence of side
effects.
, The patient has meningitis. The physician initially prescribed a water-soluble drug.
Another physician changed the order to a lipid-soluble drug. The patient is confused
about this. Which plan best resolves the patients concern?
1. Teach the patient that lipid-soluble drugs are better because of protein binding.
2. Teach the patient that lipid-soluble drugs are more effective in treating his illness.
3. Teach the patient that lipid-soluble drugs are better because they have fewer side
effects.
4. Teach the patient that lipid-soluble drugs are more effective because they are
excreted at a slower rate. correct answers Correct Answer: 2
Rationale 1: Drug molecules that are lipid soluble will usually pass through plasma
membranes by simple diffusion and more easily reach their target cells. Lipid-soluble
drugs do not necessarily have fewer side effects. Not all lipid-soluble drugs are protein
bound. Lipid solubility does not affect drug excretion.
The patient is malnourished and has a low serum albumin. The physician has ordered
aspirin, a highly protein-bound drug, for the patient. Which evaluation by the nurse best
describes the effect this will have on the patient?
1. The patient will be at risk to experience a decreased effectiveness of the drug.
2. The patient will be at risk to experience toxic effects of the drug.
3. The patients kidneys will excrete the drug at a faster rate.
4. The patients serum globulin is more important than serum albumin. correct answers
Correct Answer: 2
Rationale 1: Aspirin is a protein-bound drug. With a low albumin, there is less protein for
aspirin to bind with, making more free drug available. There may be toxic, not
decreased, effects from the drug because there is less protein for aspirin to bind with
and more free drug available. The kidney will not be able to balance the amount of the
drug and excrete it at a faster rate. Serum albumin plays a major role, more than serum
globulin.
The patient is admitted to the hospital in chronic renal failure, and is on several
medications. What best describes the nurses assessment of this patient?
1. The patients liver may compensate for renal failure; the drugs may be effective.
2. The patient may have drug toxicity from all the drugs.