What stimulates a response?
Neurotransmitter binding to receptor
T/F: neurotransmitters can be recycles to wait for another action potential
T
What are the effects of agonizing the parasympathetic NS?
- constricted pupils
- bradycardia
- bronchoconstriction
- increased gastric secretion
- emptying bowel and bladder
What are the effects of agonizing the sympathetic NS?
- tachycardia
- HTN
- bronchodilation
- dilated pupils
- shunting of blood away from skin
What is dual innervation in ANS?
Parasympathetic and sympathetic are competing to agonize the receptors.
What 3 ways does the ANS regulate physiologic processes?
- dual innervation and control
-feedback regulation
- autonomic tone
What does the baroreceptor do?
regulates blood pressure
What system helps males get an erection?
Parasympathetic
What system helps males ejaculate?
Sympathetic
What is the main neurotransmitter of the cholinergic system
Acetylcholine
What are the cholinergic receptor subtypes?
- nicotinicN
- NictoninicM
- Muscarinic
, T/F: nicotinic N cholinergic receptor subtype stimulates neuronal transmission on both PSNS and SNS
T
What does activation of the nicotinicM receptor do?
Contracts smooth muscle
What does the activation of muscarinic receptors do?
- increase glandular secretion
- contraction of bronchial, cardiac smooth muscle
What are the adrenergic receptor subtypes?
- alpha 1
- alpha 2
- beta 1
- beta 2
- dopamine
What is the function of alpha 1 receptor subtype?
- vasoconstriction
- ejaculation
- contraction of bladder neck and prostate
What is the function of alpha 2 receptor subtype?
- feedback loop to stop NE release
What is the function of Beta 1 receptor subtype
- increase HR, contractile force, and conduction
- increase renin
What is the function of Beta 2 receptor subtype?
- bronchial dilation
- relaxation of uterine muscle
- vasodilation
What is the function of dopamine in the adrenergic system?
SNS effects
If you block _________________, the breakdown of acetylcholine is blocked, leading to excessive
activation of receptors
Acetylcholinesterase
What is critical in the synthesis of NE?
Dopamine
T/F: patients on MAOIs will have more NE in their synaptic cleft
T