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Samenvatting H4 krebscyclus

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GESLAAGD IN EERSTE ZIT!!! Biochemie I wordt gegeven in 2e bachelor Diergeneeskunde, UGent door prof. Meyer. Deze samenvatting bevat zowel de voorbereiding, het mechanisme (deel 1 en 2) als de controle en regeling van de krebs. Bij de voorbereiding moet er niets zelf aangevuld worden. Bij het mechanisme zijn de belangrijkste zaken in woorden weergegeven, maar moet men de structuurformules ernaast zelf tekenen in een hokje (zelfde onderverdeling als bij voorbereiding). Door het zelf eens te tekenen onthou je er veel meer van!!! Bestaat ook in bundel (komt goedkoper uit!).

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Institution
Universiteit Gent (UGent)
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Biochemie 1








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Institution
Universiteit Gent (UGent)
Study
Bachelor in de Diergeneeskunde
Course
Biochemie 1
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Uploaded on
October 24, 2019
Number of pages
4
Written in
2019/2020
Type
Summary

Subjects

  • biochemie
  • meyer
  • chemie
  • krebscyclus
  • citroenzuurcyclus
  • g000719a
  • samenvatting

Content preview

H4: KREBS CYCLUS
VOORBEREIDING KREBS

• = pyruvaat => acetyl-CoA + CO2 via oxidatieve decarboxylatie
• Via 5 coënzymen: TPP → lipoamide → HS-CoA → FAD → NAD+

1. OXIDATIEVE DECARBOXYLATIE VIA E1
• Coënzyme TPP
• acetyl + 2 e•-transfer via OH*-ethyl-TPP,
afsplitsingCO2
• H+ tijdelijk gebonden

2. REDOX REACTIE VIA E1
• doel= recyclage TPP van E1 door oxidatie
• reductie via H- van coënzyme lipoamide van E2
• acetyl-transfer via acetyl-dihydrolipoamide


3. TRANSFER REACTIE VIA E2
• acetyl-groep van dihydrolipoamide naar HS-CoA




4. REDOX REACTIE VIA E3
• doel= recyclage lipoamide
• FAD + dihydro-lipoamide => lipoamide+ FADH2



5. REDOX REACTIE VIA E3
• doel= recyclage FAD
• NAD+ + FADH2 => FAD + NADH (+ H+)
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Diergeneeskunde UGent

Hey! Welkom bij mijn pagina. Hopelijk hebben jullie iets aan mijn samenvattingen en lesnotities, vergeet ook zeker niet mijn documenten te beoordelen!

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