8/13/24, 11:14 AM
DFDDS Special Populations
Jeremiah
Terms in this set (32)
Neonate birth to 1 month
Infant 1 month to 1 year
early childhood 1-5 years
late childhood 5-12 years
adolescence 12-17 years
usually in terms of age or weight; amoxicillin in mg/kg/day; OTC cough preps based on
how are drugs dosed for pediatric patients?
age; see package label
primary immunization route; certain antibiotics; usually given in quad of
important considerations for IM injections for
neonates/infants; water soluble drugs less likely to precipitate in muscles; 100%
pediatric patients
compliance
important considerations for rectal excellent absorption; great option for emergencies when IV unavailable (diazepam gel
administration in pediatric patients for seizures); avoids first pass effect of the liver
neonates/infants CANNOT swallow tabs; gastric juices in neonates/infants stomachs
important considerations for oral forms (tabs,
incapable of dissolving oral forms adequately; specific technique for administering
caps) in pediatric patients
liquids
thin skin (straumm corneum); microvasculature not fully-developed; not ideal for patch
important considerations for transdermal
administration; risk assessment for neonate/infant (enhanced absorption); OK in school
administration in pediatric patients
age kids; less ratio of surface area to weight compared to adults
How is pulmonary absorption affected in affected by delivery device and caregiver technique
pediatric dosing administration?
neonates/infants have different PK outcomes (ADME) than adults; dosing NOT the
PEDS SUMMARY same even for adjusted body weight; drugs require adequate clinical studies before
use in children
polypharmacy (9-12 Rx at a time), 2-4 OTC products, distinguishing between disease
What should be considered during dosing
processes and side effects, physiological changes, mutliple disease states, and
for geriatric patients?
cognitive impairment
DFDDS Special Populations
What is the effect of age on the dermal dermis thins by 20%, decreased sweating because of decrease in sweat glands; patches
function in geriatric patients? can be effective if skin still has integrity
1/2
DFDDS Special Populations
Jeremiah
Terms in this set (32)
Neonate birth to 1 month
Infant 1 month to 1 year
early childhood 1-5 years
late childhood 5-12 years
adolescence 12-17 years
usually in terms of age or weight; amoxicillin in mg/kg/day; OTC cough preps based on
how are drugs dosed for pediatric patients?
age; see package label
primary immunization route; certain antibiotics; usually given in quad of
important considerations for IM injections for
neonates/infants; water soluble drugs less likely to precipitate in muscles; 100%
pediatric patients
compliance
important considerations for rectal excellent absorption; great option for emergencies when IV unavailable (diazepam gel
administration in pediatric patients for seizures); avoids first pass effect of the liver
neonates/infants CANNOT swallow tabs; gastric juices in neonates/infants stomachs
important considerations for oral forms (tabs,
incapable of dissolving oral forms adequately; specific technique for administering
caps) in pediatric patients
liquids
thin skin (straumm corneum); microvasculature not fully-developed; not ideal for patch
important considerations for transdermal
administration; risk assessment for neonate/infant (enhanced absorption); OK in school
administration in pediatric patients
age kids; less ratio of surface area to weight compared to adults
How is pulmonary absorption affected in affected by delivery device and caregiver technique
pediatric dosing administration?
neonates/infants have different PK outcomes (ADME) than adults; dosing NOT the
PEDS SUMMARY same even for adjusted body weight; drugs require adequate clinical studies before
use in children
polypharmacy (9-12 Rx at a time), 2-4 OTC products, distinguishing between disease
What should be considered during dosing
processes and side effects, physiological changes, mutliple disease states, and
for geriatric patients?
cognitive impairment
DFDDS Special Populations
What is the effect of age on the dermal dermis thins by 20%, decreased sweating because of decrease in sweat glands; patches
function in geriatric patients? can be effective if skin still has integrity
1/2
