ASCP-CHEMISTRY SECTION
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
Aldosterone is released by the adrenal cortex upon stimulation by:
A. Renin
B. Angiotensinogen
C. Angiotenisinogen I
D. Angiotensinogen II - ANSWER D. Angiotensinogen II
Clinical Assays for tumor markers are most important for:
A. screening for the presence of cancer
B. monitoring the course of known cancer
C. confirming the absence of disease
D. identifying patients at risk for cancer - ANSWER B. Monitoring the course of known cancer
Detection of which of the following substances is most useful to monitor the course of a patient with
testicular cancer?
A. alpha-fetoprotein
B. carcinoembryonic antigen
C. prolactin
D. testosterone - ANSWER A. alpha-fetoprotein
Increased concentrations of alpha-fetoprotein (AFP) in adults are most characteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
,C. chronic active hepatitis
D. multiple myeloma - ANSWER A. hepatocellular carcinoma
Carcinoembryonic antigen (CEA) is most likely to be produced in a maignancy involving the:
A. Brain
B. Testes
C. Bone
D. Colon - ANSWER D. Colon
Which of the following is useful in the detection an management of carcinoma of the prostate?
A. total prostate-specific antigen
B. prostatic acid phosphatase
C. human chorionic gonadotropin
D. alpha-fetoprotein - ANSWER A. total prostate-specific antigen
Which of the following statements most correctly describes the utility of clinical laboratory assays for
tumor markers?
A. tumor markers are useful to screen asymptomatic patients for tumors
B. tumor markers are highly specific
C. tumor markers indicate the likelihood of an individual developing a tumor
D. tumors are useful in tracking the efficacy of treatment - ANSWER D. tumors are useful in tracking the
efficacy of treatment
Cancer antigen 125 (CA 125) is a tumor marker associated with:
A. breast carcinoma
, B. colon cancer
C. lung cancer
D. ovarian and endometrial carcinoma - ANSWER D. ovarian and endometrial carcinoma
In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA) can occur due to:
A. aspirin therapy
B. exogenous steroid use
C. benign prostatic hyperplasia
D. statin therapy (cholesterol lowering drugs) - ANSWER C. benign prostatic hyperplasia
A drug has a half-life of 6 hours. If a dose is given every 6 hours, a steady-state drug level would usually
be achieved in:
A. 3-5 hours
B. 10-12 hours
C. 24-42 hours
D. 48-50 hours - ANSWER C. 24-42 hours
The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver
metabolite of procainamide is often measured simultaneously?
A. phenobarbitol
B. quinidine
C. N-acetyl procainamide (NAPA)
D. lidocaine - ANSWER C. N-acetyl procainamide (NAPA)
Cocaine is metabolized to:
QUESTIONS AND ANSWERS WITH
SOLUTIONS 2024
Aldosterone is released by the adrenal cortex upon stimulation by:
A. Renin
B. Angiotensinogen
C. Angiotenisinogen I
D. Angiotensinogen II - ANSWER D. Angiotensinogen II
Clinical Assays for tumor markers are most important for:
A. screening for the presence of cancer
B. monitoring the course of known cancer
C. confirming the absence of disease
D. identifying patients at risk for cancer - ANSWER B. Monitoring the course of known cancer
Detection of which of the following substances is most useful to monitor the course of a patient with
testicular cancer?
A. alpha-fetoprotein
B. carcinoembryonic antigen
C. prolactin
D. testosterone - ANSWER A. alpha-fetoprotein
Increased concentrations of alpha-fetoprotein (AFP) in adults are most characteristically associated with:
A. hepatocellular carcinoma
B. alcoholic cirrhosis
,C. chronic active hepatitis
D. multiple myeloma - ANSWER A. hepatocellular carcinoma
Carcinoembryonic antigen (CEA) is most likely to be produced in a maignancy involving the:
A. Brain
B. Testes
C. Bone
D. Colon - ANSWER D. Colon
Which of the following is useful in the detection an management of carcinoma of the prostate?
A. total prostate-specific antigen
B. prostatic acid phosphatase
C. human chorionic gonadotropin
D. alpha-fetoprotein - ANSWER A. total prostate-specific antigen
Which of the following statements most correctly describes the utility of clinical laboratory assays for
tumor markers?
A. tumor markers are useful to screen asymptomatic patients for tumors
B. tumor markers are highly specific
C. tumor markers indicate the likelihood of an individual developing a tumor
D. tumors are useful in tracking the efficacy of treatment - ANSWER D. tumors are useful in tracking the
efficacy of treatment
Cancer antigen 125 (CA 125) is a tumor marker associated with:
A. breast carcinoma
, B. colon cancer
C. lung cancer
D. ovarian and endometrial carcinoma - ANSWER D. ovarian and endometrial carcinoma
In addition to carcinoma of the prostate, elevated prostate-specific antigen (PSA) can occur due to:
A. aspirin therapy
B. exogenous steroid use
C. benign prostatic hyperplasia
D. statin therapy (cholesterol lowering drugs) - ANSWER C. benign prostatic hyperplasia
A drug has a half-life of 6 hours. If a dose is given every 6 hours, a steady-state drug level would usually
be achieved in:
A. 3-5 hours
B. 10-12 hours
C. 24-42 hours
D. 48-50 hours - ANSWER C. 24-42 hours
The drug procainamide is prescribed to treat cardiac arrhythmia. What biologically active liver
metabolite of procainamide is often measured simultaneously?
A. phenobarbitol
B. quinidine
C. N-acetyl procainamide (NAPA)
D. lidocaine - ANSWER C. N-acetyl procainamide (NAPA)
Cocaine is metabolized to:
