ASCP EXAM SIMULATOR QUESTIONS
AND ANSWERS WITH SOLUTIONS 2024
Which of the following instruments measures changes in vapor pressure? - ANSWER Osmometer
What abnormal red blood cell inclusion is composed of multiple small, dark blue aggregates of
ribosomes (RNA) that are distributed throughout the RBC? - ANSWER Basophilic stippling
A situation may arise when a pathologist recognizes the presence of a parasite in an H & E - stained
section within the lumen of the appendix, as seen in the upper Image. Studies of additional fields of view
in the slide may locate the ovary and reveal the morphology of the ova contained within, as is observed
in the lower image. Based on these observations, select the presumptive identification of this parasite. -
ANSWER Enterobius vermicularis
Components of the second line of defense in the human body are - ANSWER Phagocytic cells;
complement
Which of the following is true regarding the Lutheran blood group system? - ANSWER Lu^b is a high
frequency antigen
Which of the following is a cause of metabolic alkalosis? - ANSWER Excessive vomiting
Parasites which can be found in urinary sediment include all of the following EXCEPT: - ANSWER
Plasmodium malariae
The production of neutral 17-ketosteroids is a measure of which of the following? - ANSWER Androgen
production
Which component of an electrophoresis system sets the pH? - ANSWER Buffer
Which of the following casts might be found in the urine of a healthy individual after strenuous exercise?
- ANSWER Hyaline casts and granular casts
,What are the abnormal red blood cells (RBCs) indicated by the arrows that may be suggestive of an
individual possessing the Rh null phenotype? - ANSWER Stomatocytes
Which of the following antibody types is the predominant serum antibody seen in the secondary
immune response - ANSWER IgG
Which of the following antibodies is the MOST common cause of severe hemolytic disease of the
newborn? - ANSWER Anti-D
Small intracellular gram-negative cocci were observed in a centrifuged spinal fluid sediment as presented
in the upper photomicrograph. A clinical diagnosis of meningitis was suspected. Yellow-gray colonies
after 24-hour incubation had been observed on blood agar. Based on the carbohydrate utilization tube
reactions observed in the lower photograph, what is the presumptive identification of this isolate. -
ANSWER Neisseria meningitidis
Which of the following conditions is MOST frequently associated with anti-I? - ANSWER Cold agglutinin
disease
The site most frequently used to collect bone marrow samples from adults is: - ANSWER Posterior iliac
crest
A 56-year-old woman with a history of high blood pressure and cardiovascular disease is evaluated by
her physician due to her recent loss of appetite. The doctor reviews the following test results:
Plasma creatinine = 2.4 mg/dL
Urine creatinine = 65 mg/dL
Urine volume (24 hrs) = 1400 mL
What is the estimated glomerular filtration rate for this patient? - ANSWER (Urine creatinine / plasma
creatinine) x (volume / minute) = glomerular filtration rate (mL/min)
*in order to solve this problem, the 24 hour urine must be converted into minutes. 1440 minutes should
be used as the denominator in the volume component.
So...for this patient, the calculation would be:
( 65 mg/dL / 2.4 mg/dL ) X ( 1400 mL / 1440 min ) = (27.083) X (0.972 mL/min) =
= 26.32 mL/min
, All of the listed disorders are organ non-specific autoimmune diseases EXCEPT: - ANSWER Hashimoto's
disease
What is the main function of thrombocytes? - ANSWER To assist in the coagulation process
A lipid panel consists of which of the following tests? - ANSWER Cholesterol, Lipoprotein, HDL,
Triglycerides
Which Aspergillus species show biseriate with phialides covering the entire surface of a spherical vesicle
with black conidia as microscopic morphological features? - ANSWER Aspergillus niger
An increased number of the cells seen in the image, upon microscopic examination of urine is termed: -
ANSWER Hematuria
The VDRL and RPR are used to provide presumptive identification of which infection? - ANSWER Syphilis
What is the explanation for a discrepancy in the following front type and back type in a newborn?
Anti-A = neg
Anti-B = neg
A1 cells = neg
B cells = neg - ANSWER The baby's antibodies are undeveloped.
What urine contaminant could cause a falsely elevated level of urinary albumin, thus giving the false
interpretation of kidney damage? - ANSWER Blood from menstruation
If Jka is showing dosage, how might reactions on an antibody panel appear? - ANSWER Weaker if
heterozygous for Jka and Jkb
Which of the following patients is most at risk for hyperosmolar nonketotic coma? - ANSWER A 70-year-
old type 2 diabetic patient
AND ANSWERS WITH SOLUTIONS 2024
Which of the following instruments measures changes in vapor pressure? - ANSWER Osmometer
What abnormal red blood cell inclusion is composed of multiple small, dark blue aggregates of
ribosomes (RNA) that are distributed throughout the RBC? - ANSWER Basophilic stippling
A situation may arise when a pathologist recognizes the presence of a parasite in an H & E - stained
section within the lumen of the appendix, as seen in the upper Image. Studies of additional fields of view
in the slide may locate the ovary and reveal the morphology of the ova contained within, as is observed
in the lower image. Based on these observations, select the presumptive identification of this parasite. -
ANSWER Enterobius vermicularis
Components of the second line of defense in the human body are - ANSWER Phagocytic cells;
complement
Which of the following is true regarding the Lutheran blood group system? - ANSWER Lu^b is a high
frequency antigen
Which of the following is a cause of metabolic alkalosis? - ANSWER Excessive vomiting
Parasites which can be found in urinary sediment include all of the following EXCEPT: - ANSWER
Plasmodium malariae
The production of neutral 17-ketosteroids is a measure of which of the following? - ANSWER Androgen
production
Which component of an electrophoresis system sets the pH? - ANSWER Buffer
Which of the following casts might be found in the urine of a healthy individual after strenuous exercise?
- ANSWER Hyaline casts and granular casts
,What are the abnormal red blood cells (RBCs) indicated by the arrows that may be suggestive of an
individual possessing the Rh null phenotype? - ANSWER Stomatocytes
Which of the following antibody types is the predominant serum antibody seen in the secondary
immune response - ANSWER IgG
Which of the following antibodies is the MOST common cause of severe hemolytic disease of the
newborn? - ANSWER Anti-D
Small intracellular gram-negative cocci were observed in a centrifuged spinal fluid sediment as presented
in the upper photomicrograph. A clinical diagnosis of meningitis was suspected. Yellow-gray colonies
after 24-hour incubation had been observed on blood agar. Based on the carbohydrate utilization tube
reactions observed in the lower photograph, what is the presumptive identification of this isolate. -
ANSWER Neisseria meningitidis
Which of the following conditions is MOST frequently associated with anti-I? - ANSWER Cold agglutinin
disease
The site most frequently used to collect bone marrow samples from adults is: - ANSWER Posterior iliac
crest
A 56-year-old woman with a history of high blood pressure and cardiovascular disease is evaluated by
her physician due to her recent loss of appetite. The doctor reviews the following test results:
Plasma creatinine = 2.4 mg/dL
Urine creatinine = 65 mg/dL
Urine volume (24 hrs) = 1400 mL
What is the estimated glomerular filtration rate for this patient? - ANSWER (Urine creatinine / plasma
creatinine) x (volume / minute) = glomerular filtration rate (mL/min)
*in order to solve this problem, the 24 hour urine must be converted into minutes. 1440 minutes should
be used as the denominator in the volume component.
So...for this patient, the calculation would be:
( 65 mg/dL / 2.4 mg/dL ) X ( 1400 mL / 1440 min ) = (27.083) X (0.972 mL/min) =
= 26.32 mL/min
, All of the listed disorders are organ non-specific autoimmune diseases EXCEPT: - ANSWER Hashimoto's
disease
What is the main function of thrombocytes? - ANSWER To assist in the coagulation process
A lipid panel consists of which of the following tests? - ANSWER Cholesterol, Lipoprotein, HDL,
Triglycerides
Which Aspergillus species show biseriate with phialides covering the entire surface of a spherical vesicle
with black conidia as microscopic morphological features? - ANSWER Aspergillus niger
An increased number of the cells seen in the image, upon microscopic examination of urine is termed: -
ANSWER Hematuria
The VDRL and RPR are used to provide presumptive identification of which infection? - ANSWER Syphilis
What is the explanation for a discrepancy in the following front type and back type in a newborn?
Anti-A = neg
Anti-B = neg
A1 cells = neg
B cells = neg - ANSWER The baby's antibodies are undeveloped.
What urine contaminant could cause a falsely elevated level of urinary albumin, thus giving the false
interpretation of kidney damage? - ANSWER Blood from menstruation
If Jka is showing dosage, how might reactions on an antibody panel appear? - ANSWER Weaker if
heterozygous for Jka and Jkb
Which of the following patients is most at risk for hyperosmolar nonketotic coma? - ANSWER A 70-year-
old type 2 diabetic patient
