BIOMG 3300 Unit 13 Objectives Questions with Correct Answers

BIOMG 3300 Unit 13 Objectives Questions with
Correct Answers
where is glycogen normally found? Correct Answer-The liver


Which end is glycogen extended? Correct Answer-Non reducing end


glycogen phosphorylase kinase Correct Answer-breaks glycogen into
glucose-1 and a shortened glycogen chain via phosphorylysis rxn


active form of glycogen phosphorylase kinase Correct Answer-
phosphorylase a (phosphorylated)


Inactive form of glycogen phosphorylase Correct Answer-phosphorylase
b (dephosphorylated)


phosphorolysis rxn Correct Answer-breaking a bond by adding a
phosphate group. Allows some of the energy from the bond to be stored


Why are sugar nucleotides good substrates? Correct Answer--formation
is irreversible
-they can form many interactions with enzymes, leading to an increase
in stability
-they have good LG
-cells can use nucleotide groups to set the sugars apart for a particular
purpose

, reaction creating UDP-sugar Correct Answer--uses the enzyme UDP-
sugar pyrophosphoylase
-produces pyrophosophate, whose hydrolysis drives the rxn


Epinephrine signal transduction pathway Correct Answer--epinephrine
binds to GPCR
-G alpha binds GP and activates adenylyl cyclase
-adenylyl cyclase produces cAMP
-cAMP activates PKA, which activates enzyme targets


GPCR Correct Answer-has 7 transmembrane domains, stis in
membrane. Can bind epinephrine or glucagon


adenylyl cyclase Correct Answer-produces cMAP when activated by
Gs-GTP


PKA Correct Answer-phosphorylates the Ser or Thr on glycogen
phosphorylase kinase


Kinase BARK (GRK2) Correct Answer-contributes to the
desensitization of the GCPR by phosphorylating Ser residues of the C
terminus