Chapter 14 Microbiology UTA Tholen;
Questions and Answers % Correct
Chemotherapy Correct answer-drugs that target living cells and tissues (includes
microbes
Antimicrobials Correct answer-Used in 350 AD (even though they didn't know how the
chemical worked)
Antimicrobials were mostly obtained through Correct answer-consumption of plants and
fermented products (i.e. beer)
First drugs were developed by science in Correct answer-early 1900s
Paul Ehrlich Correct answer-scanned through 600 arsenic compounds to find cure for
syphilis without killing host
Syphilis compound was derived from Correct answer-Treponema pallidum and
established modern drug discovery methods
Joseph Klarer, Fritz Mietzch, and Gerhard Domagk Correct answer-used synthetic dye,
prontosil, to treat strep infections
The first synthetic antimicrobial was Correct answer-Prontosil; opened door for all "sulfa"
drugs
, Chapter 14 Microbiology UTA Tholen;
Questions and Answers % Correct
Alex Fleming Correct answer-accidentally discovered antibiotic from Penicillum notatum
growing on bacterial agar plate
Penicillum Correct answer-1st natural antibiotic
Bactericidal Correct answer-kills microbes
Bacteriostatic Correct answer-halts growth of microbes
Narrow Spectrum of Chemotherapy Drugs Correct answer-BEST CHOICE; targets specific
group of microbes
Broad Spectrum of Chemotherapy Drugs Correct answer-targets wide variety
Downside to Broad Spectrum Correct answer-superinfection
Superinfection Correct answer-1) Normal microbiota keeps opportunistic pathogens in
check
2) Broad-spectrum antibiotics kill nonresistant cells
3) Drug-resistant pathogens proliferate and can cause a superinfection
Questions and Answers % Correct
Chemotherapy Correct answer-drugs that target living cells and tissues (includes
microbes
Antimicrobials Correct answer-Used in 350 AD (even though they didn't know how the
chemical worked)
Antimicrobials were mostly obtained through Correct answer-consumption of plants and
fermented products (i.e. beer)
First drugs were developed by science in Correct answer-early 1900s
Paul Ehrlich Correct answer-scanned through 600 arsenic compounds to find cure for
syphilis without killing host
Syphilis compound was derived from Correct answer-Treponema pallidum and
established modern drug discovery methods
Joseph Klarer, Fritz Mietzch, and Gerhard Domagk Correct answer-used synthetic dye,
prontosil, to treat strep infections
The first synthetic antimicrobial was Correct answer-Prontosil; opened door for all "sulfa"
drugs
, Chapter 14 Microbiology UTA Tholen;
Questions and Answers % Correct
Alex Fleming Correct answer-accidentally discovered antibiotic from Penicillum notatum
growing on bacterial agar plate
Penicillum Correct answer-1st natural antibiotic
Bactericidal Correct answer-kills microbes
Bacteriostatic Correct answer-halts growth of microbes
Narrow Spectrum of Chemotherapy Drugs Correct answer-BEST CHOICE; targets specific
group of microbes
Broad Spectrum of Chemotherapy Drugs Correct answer-targets wide variety
Downside to Broad Spectrum Correct answer-superinfection
Superinfection Correct answer-1) Normal microbiota keeps opportunistic pathogens in
check
2) Broad-spectrum antibiotics kill nonresistant cells
3) Drug-resistant pathogens proliferate and can cause a superinfection
