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What does the acronym IACUC stand for? CORRECT ANSWER-Institutional Animal Care
and Use Committee
Which task is NOT a function of the IACUC? CORRECT ANSWER-Assist with writing the
basic science portions of a grant application.
Which of the following institutions must follow PHS guidelines for animal research?
CORRECT ANSWER-All institutions that accept PHS funding
Which organization is responsible for monitoring institutional compliance with PHS Policy?
CORRECT ANSWER-Office of Laboratory Animal Welfare
Which of the following is a role of AAALAC International? CORRECT ANSWER-To conduct
voluntary evaluations of institutional animal care and use programs.
Which of the following is helpful to the IACUC when reviewing an animal protocol?
CORRECT ANSWER-The use of a flowchart to illustrate complex experimental designs
Which of the following statements about using a statistical analysis to justify animal numbers is
TRUE? CORRECT ANSWER-A statistical analysis should be used whenever possible.
, Working with the IACUC; Questions & Answers Latest
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Which of the following statements concerning selection of species for research is FALSE?
CORRECT ANSWER-Vertebrate species should be used instead of invertebrates whenever
possible.
A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought
process and a thorough understanding of the number, species, housing and transport
requirements of animals proposed for use in research studies CORRECT ANSWER-True
Which of the following is NOT an example of reduction per the three Rs of Russell and Burch?
CORRECT ANSWER-The use of a new anesthetic that provides better induction and a
shorter recovery period
The Animal Welfare Regulations require the IACUC to do what two things regarding
alternatives? CORRECT ANSWER-Ensure that the principal investigator has considered
alternatives to painful or distressing procedures, and review a written assurance that
alternatives are not available.
The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro
Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily
interested in what area? CORRECT ANSWER-Performing or sponsoring research into
alternatives to animal use for research and testing.
Which of the following is an example of refinement per the three Rs of Russell and Burch?
CORRECT ANSWER-The use of a new blood collection technique that causes less pain
and distress