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The NIH Guidelines for Recombinant DNA and Gene Transfer do not apply to which of the
following types of experiments?
Inoculation of recombinant infectious agents into animals
Inoculation of non-recombinant infectious agents into animals
Inoculation of recombinant infectious agents into mice and rats
Laboratory use of recombinant infectious agents for in vitro workThe Animal Welfare Act and
Regulations currently apply to which of the following animals? CORRECT ANSWER-
inoculation of nonrecumbent infectious agents in animals
With the gradual displacement method of carbon dioxide inhalation, what is the optimal
percentage of air per minute to be replaced with CO2?
35%-45%
50%-70%
5%-9%
10%-30% CORRECT ANSWER-10-30%
Which of the following statements about postoperative care records is TRUE? CORRECT
ANSWER-For rodents, postoperative records for the group may be kept on cage cards or in
laboratory notebooks.
Which of the following statements concerning adjuvants is true?
Alternatives to CFA and IFA adjuvants are more inflammatory, but less expensive.
Less inflammatory alternatives to the use of CFA and IFA adjuvants are available commercially.
, Working with IACUC Study guide; Questions & Answers
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PHS Policy prohibits the use of CFA and IFA adjuvants.
The Animal Welfare regulations prohibit the use of CFA and IFA adjuvants. CORRECT
ANSWER-Less inflammatory alternatives to the use of CFA and IFA adjuvants are available
commercially.
According to the Guide, social animals should be housed in pairs or groups. Which of the
following is NOT a good justification for housing animals by themselves?
Health problems in an animal
Behavioral reasons such as aggression
Convenience of the research and husbandry staff
Scientific reasons CORRECT ANSWER-Convenience of the research and husbandry staff
Which statement does <strong>NOT</strong> apply to experimental surgery on animals?
CORRECT ANSWER-The need for sterile technique in survival surgeries is at the discretion
of the investigator.
Which of the following is true of the primate psychological enrichment program mandated by
the Animal Welfare Act and Regulations?
The veterinarian cannot exempt an animal, even for medical reasons.
The IACUC can exempt an animal for scientific reasons, if documented in the approved protocol.
Primates must be enrolled in the program and cannot be exempted.
The animal care staff can exempt an animal for scientific reasons. CORRECT ANSWER-The
IACUC can exempt an animal for scientific reasons, if documented in the approved protocol.