Immunology Final Exam; Questions & Answers
100% Correct
Which of the following is an example of a primary lymphoid organ?
A) Lymph node
B) Spleen
C) Bone Marrow
D) MALT Answer-Bone marrow
MALT stands for what? Answer-Mucosal associated lymphoid tissue
All of the following are features of adaptive immunity, except:
A) Exhibits immunological memory
B) represents the first line of defense against foreign invaders
C) Specific for particular microbes
D) Capable of responding to a wide variety of pathogens Answer-B) represents the first
line of defense against foreign invaders
Which of the following cells express cells express MHC class II molecules?
A) Helper T cells
B) Macrophages
C) Cytotoxic T cells
D) Natural killer cells Answer-B) Macrophages
,Immunology Final Exam; Questions & Answers
100% Correct
Describe the Journey of a helper T cell: Answer-Maturation in the thymus; migration to
lymph node; activation; migration to infected tissues
All of the following are true regarding antibody structure, except:
A) Composed of four polypeptide chains
B) Constant region binds to antigen
C) Complimentary determining regions contain hypervariable amino acids
D) Region that mediates effector function contains part of both the heavy and light chain
Answer-B) Constant region binds to antigen
All of the following are similarities between B cell and T cell receptors, except:
A) Both contain transmembrane segments
B) Each is comprised of at least one immunoglobulin domain
C) Both can exist as membrane-bound or secreted forms
D) Each is complexed with a signaling molecule Answer-C) Both can exist as membrane-
bound or secreted forms
Which of the following cytokines is produced by macrophages?
A) IL-1
B) IL-2
C) Interferon gamma (IFN-y)
,Immunology Final Exam; Questions & Answers
100% Correct
D) all of the above Answer-A) IL-1
Which of the following is true regarding cytokine receptor signaling?
A) Calcineurin directly results in increased cytoplasmic calcium ion concentration
B) The breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) results in DAG and PKC
C) The Src family contains phosphatases that dephosphorylate tyrosine residues
D) Initiation of the MAP kinase pathway by RAS ultimately results in activation of the
transcription factor AP-1 Answer-D) Initiation of the MAP kinase pathway by RAS
ultimately results in activation of the transcription factor AP-1
A cytokine can produce different results depending on which target cell it is bound to. (True or
False) Answer-True
Specific term to the portion of antigen that is recognized by an antibody or T cell receptor.
A) Immunogen
B) Pathogen
C) Hapten
D) None of the above Answer-D) None of the above
Which of the following is an example of a pro-inflammatory cytokine?
A) Psoriasin
, Immunology Final Exam; Questions & Answers
100% Correct
B) C3a
C) IL-1B (beta)
D) All of the above Answer-C) IL-1B (beta)
Which of the following cells express cells express MHC class II molecules?
A) Helper T cells
B) Macrophages
C) Cytotoxic T cells
D) Natural killer cells Answer-B) Macrophages
All of the following are true regarding tool-like receptors, except:
A)A type of pattern recognition receptor
B) Exists as dimers
C) located exclusively in the cytosol
D) capable of activating multiple signal pathways in a cell Answer-C) located exclusively in
the cytosol
List one benefit of normal flora: Answer--they are able to break down/synthesize
substances our body wouldn't be able to naturally
Which of the following is true regarding RIG-1-like receptors?
100% Correct
Which of the following is an example of a primary lymphoid organ?
A) Lymph node
B) Spleen
C) Bone Marrow
D) MALT Answer-Bone marrow
MALT stands for what? Answer-Mucosal associated lymphoid tissue
All of the following are features of adaptive immunity, except:
A) Exhibits immunological memory
B) represents the first line of defense against foreign invaders
C) Specific for particular microbes
D) Capable of responding to a wide variety of pathogens Answer-B) represents the first
line of defense against foreign invaders
Which of the following cells express cells express MHC class II molecules?
A) Helper T cells
B) Macrophages
C) Cytotoxic T cells
D) Natural killer cells Answer-B) Macrophages
,Immunology Final Exam; Questions & Answers
100% Correct
Describe the Journey of a helper T cell: Answer-Maturation in the thymus; migration to
lymph node; activation; migration to infected tissues
All of the following are true regarding antibody structure, except:
A) Composed of four polypeptide chains
B) Constant region binds to antigen
C) Complimentary determining regions contain hypervariable amino acids
D) Region that mediates effector function contains part of both the heavy and light chain
Answer-B) Constant region binds to antigen
All of the following are similarities between B cell and T cell receptors, except:
A) Both contain transmembrane segments
B) Each is comprised of at least one immunoglobulin domain
C) Both can exist as membrane-bound or secreted forms
D) Each is complexed with a signaling molecule Answer-C) Both can exist as membrane-
bound or secreted forms
Which of the following cytokines is produced by macrophages?
A) IL-1
B) IL-2
C) Interferon gamma (IFN-y)
,Immunology Final Exam; Questions & Answers
100% Correct
D) all of the above Answer-A) IL-1
Which of the following is true regarding cytokine receptor signaling?
A) Calcineurin directly results in increased cytoplasmic calcium ion concentration
B) The breakdown of phosphatidylinositol 4,5-bisphosphate (PIP2) results in DAG and PKC
C) The Src family contains phosphatases that dephosphorylate tyrosine residues
D) Initiation of the MAP kinase pathway by RAS ultimately results in activation of the
transcription factor AP-1 Answer-D) Initiation of the MAP kinase pathway by RAS
ultimately results in activation of the transcription factor AP-1
A cytokine can produce different results depending on which target cell it is bound to. (True or
False) Answer-True
Specific term to the portion of antigen that is recognized by an antibody or T cell receptor.
A) Immunogen
B) Pathogen
C) Hapten
D) None of the above Answer-D) None of the above
Which of the following is an example of a pro-inflammatory cytokine?
A) Psoriasin
, Immunology Final Exam; Questions & Answers
100% Correct
B) C3a
C) IL-1B (beta)
D) All of the above Answer-C) IL-1B (beta)
Which of the following cells express cells express MHC class II molecules?
A) Helper T cells
B) Macrophages
C) Cytotoxic T cells
D) Natural killer cells Answer-B) Macrophages
All of the following are true regarding tool-like receptors, except:
A)A type of pattern recognition receptor
B) Exists as dimers
C) located exclusively in the cytosol
D) capable of activating multiple signal pathways in a cell Answer-C) located exclusively in
the cytosol
List one benefit of normal flora: Answer--they are able to break down/synthesize
substances our body wouldn't be able to naturally
Which of the following is true regarding RIG-1-like receptors?
