Complete BOC ASCP prep
Questions and Answers
151) What is the formula for calculating the dilution of a solution.
✓~ V1 x C1 = V2 x C2
V1 is the volume
C1 is concentration of sol 1
V2 is vol of the diluted solution
C2 is conc of diluted solution
241) To confirm a serum antibody specificity identified as anti-P1, a neutralization
study was performed and the following results obtained:
serum + P1 substance = NEGATIVE
serum + saline = NEGATIVE
What conclusion can be made from these results.
,✓~ anti-P1 cannot be confirmed due to the results of the negative control
(For neutralization studies to be valid, the saline dilutional control must be reactive. Since
neutralization studies involve adding a substance to the patient's plasma, nonreactivity in
test tubes may be due to simple dilution. The saline control acts as the dilutional control and
must be reactive. When the saline control is reactive, then if the tube with the substance is
nonreactive, the interpretation that neutralization has occurred is made. If it is reactive,
neutralization did not occur.)
278) The most sensitive test for the initial diagnosis of cryptococcal disease is:
✓~ Cryptococcal latex antigen test is more sensitive than staining methods
308) Which of the following factors is used only in the extrinsic coagulation pathway?
✓~ Factor VII
8) Shown above is a Levy-Jennings quality control chart, which represents control
values for 13 consecutive analyses for a particular serum constituent. If the 14th
value is below the —2 SD limit, which of the following should be done?
✓~ analysis system should be checked for a deteriorating component
202) A 1 yr. old girl with a hyperlipoproteinemia and lipase deficiency has the
following lipid profile:
cholesterol = 300 mg/dL
LDL increased
,HDL decreased
triglycerides = 200 mg/dL
chylomicrons present
A serum specimen from this patient that was refrigerated overnight would most likely
be:
✓~ The chylomicrons, present as a thick homogenous cream layer, may be observed
floating at the plasma surface.
1) Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
✓~ <45mg/dL (<2.5mmol/L)
3) The preparation of a patient for standard glucose tolerance testing should include:
✓~ high carb diet for 3 days
4) If a fasting glucose was 90 mg/dL, which of the following 2 hr. postprandial
glucose result would most closely represent normal glucose metabolism?
✓~ 100 mg/dL (5.5 mmol/L)
5) A healthy person with a blood glucose of 80 mg/dL (4.4 mmol/L) would have a
simultaneously determined cerebrospinal fluid glucose value of:
✓~ 50 mg/dL (2.3 mmol/L)
, 6) A 25 yr. old man became nauseated and vomited 90 mins after receiving a
standard 75 g carbohydrate dose for an oral glucose tolerance test. The best course
of action is to:
✓~ draw blood for glucose and discontinue the test
7) Cerebrospinal fluid for glucose assay should be:
✓~ analyzed immediately
8) Which of the following 2 hr. postprandial glucose values demonstrates
unequivocal hyperglycemia diagnostic for diabetes mellitus?
✓~ 200 mg/dL (11.0 mmol/L)
10) A 45 yr. old woman has a fasting serum glucose concentration of 95 mg/dL (5.2
mmol/L) and a 2 hr. postprandial glucose concentration of 105 mg/dL (5.8 mmol/L).
The statement which best describes this patient's fasting serum glucose
concentration is:
✓~ normal; reflecting glycogen breakdown by the liver
9) Serum levels that define hypoglycemia in pre-term or low birth weight infants are:
✓~ lower than adults
Questions and Answers
151) What is the formula for calculating the dilution of a solution.
✓~ V1 x C1 = V2 x C2
V1 is the volume
C1 is concentration of sol 1
V2 is vol of the diluted solution
C2 is conc of diluted solution
241) To confirm a serum antibody specificity identified as anti-P1, a neutralization
study was performed and the following results obtained:
serum + P1 substance = NEGATIVE
serum + saline = NEGATIVE
What conclusion can be made from these results.
,✓~ anti-P1 cannot be confirmed due to the results of the negative control
(For neutralization studies to be valid, the saline dilutional control must be reactive. Since
neutralization studies involve adding a substance to the patient's plasma, nonreactivity in
test tubes may be due to simple dilution. The saline control acts as the dilutional control and
must be reactive. When the saline control is reactive, then if the tube with the substance is
nonreactive, the interpretation that neutralization has occurred is made. If it is reactive,
neutralization did not occur.)
278) The most sensitive test for the initial diagnosis of cryptococcal disease is:
✓~ Cryptococcal latex antigen test is more sensitive than staining methods
308) Which of the following factors is used only in the extrinsic coagulation pathway?
✓~ Factor VII
8) Shown above is a Levy-Jennings quality control chart, which represents control
values for 13 consecutive analyses for a particular serum constituent. If the 14th
value is below the —2 SD limit, which of the following should be done?
✓~ analysis system should be checked for a deteriorating component
202) A 1 yr. old girl with a hyperlipoproteinemia and lipase deficiency has the
following lipid profile:
cholesterol = 300 mg/dL
LDL increased
,HDL decreased
triglycerides = 200 mg/dL
chylomicrons present
A serum specimen from this patient that was refrigerated overnight would most likely
be:
✓~ The chylomicrons, present as a thick homogenous cream layer, may be observed
floating at the plasma surface.
1) Following overnight fasting, hypoglycemia in adults is defined as a glucose of:
✓~ <45mg/dL (<2.5mmol/L)
3) The preparation of a patient for standard glucose tolerance testing should include:
✓~ high carb diet for 3 days
4) If a fasting glucose was 90 mg/dL, which of the following 2 hr. postprandial
glucose result would most closely represent normal glucose metabolism?
✓~ 100 mg/dL (5.5 mmol/L)
5) A healthy person with a blood glucose of 80 mg/dL (4.4 mmol/L) would have a
simultaneously determined cerebrospinal fluid glucose value of:
✓~ 50 mg/dL (2.3 mmol/L)
, 6) A 25 yr. old man became nauseated and vomited 90 mins after receiving a
standard 75 g carbohydrate dose for an oral glucose tolerance test. The best course
of action is to:
✓~ draw blood for glucose and discontinue the test
7) Cerebrospinal fluid for glucose assay should be:
✓~ analyzed immediately
8) Which of the following 2 hr. postprandial glucose values demonstrates
unequivocal hyperglycemia diagnostic for diabetes mellitus?
✓~ 200 mg/dL (11.0 mmol/L)
10) A 45 yr. old woman has a fasting serum glucose concentration of 95 mg/dL (5.2
mmol/L) and a 2 hr. postprandial glucose concentration of 105 mg/dL (5.8 mmol/L).
The statement which best describes this patient's fasting serum glucose
concentration is:
✓~ normal; reflecting glycogen breakdown by the liver
9) Serum levels that define hypoglycemia in pre-term or low birth weight infants are:
✓~ lower than adults
