Pharm Exam 3 Questions And Answers
Testosterone is produced in the ______ cells of the testes
A) sertoli
B) leydig
C) theca
D) granulosa
- correct answer ✅B) leydig
T/F: 95% of testosterone production is via the adrenal glands
- correct answer ✅False, from the leydig cells in the testes
5% from the adrenal glands
T/F: The majority of circulating testosterone is bound to Sex-hormone
binding globulin (SHBG)
- correct answer ✅True, nearly 65%.
33% = bound to albumin
2% = free
Which of the following factors does not increase SHBG?
A) Estrogen
B) thyroid hormone
,Pharm Exam 3 Questions And Answers
C) Liver cirrhosis
D) Growth hormone
- correct answer ✅D) Growth hormone
Estrogen, thyroid hormone and liver cirrhosis all increase SHBG,
meaning they decrease free testosterone availability.
GH, androgens and obesity all decrease SHBH.
The major androgen in peripheral tissues such as the prostate, penis,
scrotum and skin in:
A) testosterone
B) dihydrogentestosterone (DHT)
C) Androstenedione
D) dehydroepiandrosterone (DHEA)
- correct answer ✅B) dihydrogentestosterone (DHT)
this is the most potent
In peripheral tissues, testosterone is converted to DHT by:
,Pharm Exam 3 Questions And Answers
A) P450 Aromatase
B) 21-a hydroxylase
C) 5-a reductase
- correct answer ✅C) 5-a reductase
Testosterone is converted to estradiol in fat, liver and bone by:
A) P450 Aromatase
B) 21-a hydroxylase
C) 5-a reductase
D) 17-a hydroxylase
- correct answer ✅A) P450 Aromatase
which is an effect of testosterone?
A) Development of male fetus
B) Growth of penis
C) Development of facial and pubic hair
D) Enlarged muscle mass
E) all of the above
- correct answer ✅E) all of the above
, Pharm Exam 3 Questions And Answers
Which of the following most likely causes acne, male-pattern baldness
and prostate growth in males?
A) testosterone
B) DHEA
C) Estradiol
D) DHT
- correct answer ✅D) DHT
it is extremely potent
Which of the following helps maintain normal bone density in men?
a) testosterone
B) DHEA
C) Estradiol
D) DHT
- correct answer ✅C) Estradiol
Bone has aromatase which converts testosterone to estradiol
The functioning androgen in liver and muscle is:
Testosterone is produced in the ______ cells of the testes
A) sertoli
B) leydig
C) theca
D) granulosa
- correct answer ✅B) leydig
T/F: 95% of testosterone production is via the adrenal glands
- correct answer ✅False, from the leydig cells in the testes
5% from the adrenal glands
T/F: The majority of circulating testosterone is bound to Sex-hormone
binding globulin (SHBG)
- correct answer ✅True, nearly 65%.
33% = bound to albumin
2% = free
Which of the following factors does not increase SHBG?
A) Estrogen
B) thyroid hormone
,Pharm Exam 3 Questions And Answers
C) Liver cirrhosis
D) Growth hormone
- correct answer ✅D) Growth hormone
Estrogen, thyroid hormone and liver cirrhosis all increase SHBG,
meaning they decrease free testosterone availability.
GH, androgens and obesity all decrease SHBH.
The major androgen in peripheral tissues such as the prostate, penis,
scrotum and skin in:
A) testosterone
B) dihydrogentestosterone (DHT)
C) Androstenedione
D) dehydroepiandrosterone (DHEA)
- correct answer ✅B) dihydrogentestosterone (DHT)
this is the most potent
In peripheral tissues, testosterone is converted to DHT by:
,Pharm Exam 3 Questions And Answers
A) P450 Aromatase
B) 21-a hydroxylase
C) 5-a reductase
- correct answer ✅C) 5-a reductase
Testosterone is converted to estradiol in fat, liver and bone by:
A) P450 Aromatase
B) 21-a hydroxylase
C) 5-a reductase
D) 17-a hydroxylase
- correct answer ✅A) P450 Aromatase
which is an effect of testosterone?
A) Development of male fetus
B) Growth of penis
C) Development of facial and pubic hair
D) Enlarged muscle mass
E) all of the above
- correct answer ✅E) all of the above
, Pharm Exam 3 Questions And Answers
Which of the following most likely causes acne, male-pattern baldness
and prostate growth in males?
A) testosterone
B) DHEA
C) Estradiol
D) DHT
- correct answer ✅D) DHT
it is extremely potent
Which of the following helps maintain normal bone density in men?
a) testosterone
B) DHEA
C) Estradiol
D) DHT
- correct answer ✅C) Estradiol
Bone has aromatase which converts testosterone to estradiol
The functioning androgen in liver and muscle is:
