replication Gene
mutations proofreading
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Prokaryotes and
Denning [Date] [Course title]
, Describe the experiments that led to the discovery of DNA as the hereditary meterial - Correct Ans: 1.
The bacterial transforming principle by Griffith:
found that nonvirulent R-strain takes up a transforming principle from the virulent heat-killed S-strain.
This allowed the R-strain to transform into S-strain becoming virulent.
2. Avery-MacLeod-McCarty Experiment:
S-strain filtrate was made and treated with RNase, Dnase, Protease, and Carboase. Those were then
treated with the R-strain and found that the only dample containing both both strains was the one with
Dnase.
3. The Hershey Chase experiment:
Officially concluded that DNA was genetic material from work with phages.
What were the conclusions for the three experiments that led to DNA being the hereditary meterial? -
Correct Ans: 1. The bacterial transforming principle by Griffith:
found that nonvirulent R-strain takes up a transforming principle from the virulent heat-killed S-strain.
This allowed the R-strain to transform into S-strain becoming virulent.
2. Avery-MacLeod-McCarty Experiment:
DNA is the transforming factor
3. The Hershey-Chase Experiment:
DNA is the genetic material
What are the building blocks of DNA - Correct Ans: nucleotides
What are nucleotides composed of? - Correct Ans: 5 carbon sugar, phosphate group, nitrogenous base
A, T, G, C
Nucleotides combine via___ - Correct Ans: covalent bonds
Nucleotides are assembled into polynucleotide chains by:
a. endonuclease
b. DNA pol.
c. RNA pol.