General Genetics
Questions and Complete
Solutions Graded A+
Denning [Date] [Course title]
, components of a nucleotide - Correct Ans: phosphate group, 5 carbon sugar, nitrogenous base
types of nitrogenous bases - Correct Ans: purines and pyrimidines
1' (deoxyribose carbon atom numbering system) - Correct Ans: the carbon attached to the nitrogenous
base
2' (deoxyribose carbon atom numbering system) - Correct Ans: the deoxy carbon - only hydrogens
attached
3' (deoxyribose carbon atom numbering system) - Correct Ans: carries the hydroxyl group
4' (deoxyribose carbon atom numbering system) - Correct Ans: binds to the O which binds to the 1' to
make the ring
5' (deoxyribose carbon atom numbering system) - Correct Ans: carries the phosphate group
DNA strand polarity - Correct Ans: Each strand of DNA has distinct 5' and 3' ends creating polarity within
the backbone.
5' will have an -OH or phosphate group bonded to C-5' of the sugar, while the 3' end has a free -OH on C-
3 of the sugar.
Rules to apply - Correct Ans: pyrimidine vs purine
A=T, C=G
3 hyrdogen bonds (C-G), 2 hydrogen bonds (A-T)
5' carbon vs 3' carbon
strands are anti-parallel
Chargaff's Rule - Correct Ans: ratios are 1:1