Biological Psychology
, pp. 23-60 ch. 2
i
Genetics and Evolution 2
EVOLUTION THE EVOLUTION OF HUMANS
I :÷ ÷"l÷ ÷ ÷:÷÷ ÷÷÷÷÷÷:
÷÷ ÷
- -
-
-
Charles Darwin :
common ancestor
f--
Life in the water
↳
adaptations via natural selection ↳ evolved into amphibians
↳ survival of the fittest ↳ evolved into reptiles
→
further adaptation to life on land
-
Evidence for evolution
↳
biogeography -
Mammals evolved from reptiles n 180 million
years ago
→ best fit for their environment
organisms are the
↳ humans stem from order of primates
:÷ ÷ ÷ ÷ ÷ ÷ ÷ ÷ ÷ ÷
↳ Molecular biology → 50000
years ago migrated out of Africa
of genetic
"
→ strands '
'
we share common → out of Africa hypothesis
materialwithotherorganis.gs -
Human brain
EVOLUTIONARY PSYCHOLOGY
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↳ size and volume greater than in other species
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.
.
↳ first humans tracked down via Y -
why is this maladaptive behaviour still present
-
andwharwasitsoriginalreasonforbein#
4
5
QUALITATIVE TRAITS QUANTITATIVE TRAIT T
- # 1-
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f. :÷ ÷ f÷ ÷ ÷: ÷ ÷ ÷
-
influenced by a single gene Influenced by
multiple genes
-
-
follow a simple pattern of inheritance Ce g Mendelian inheritance) Don 't follow simple patterns of inheritance
- -
.
-
typically unaffected by environment ↳ more variable and less predictable
Factors that may alter the pattern of inheritance Et pressed
-
along a continuum
-
'
→ Genetic heterogeneity ↳ e.g ADHD
.
÷÷÷÷÷÷÷÷÷÷÷÷÷÷÷÷÷÷÷
→
-
disease completely or
partially
↳ Mosaicism
→ not all cells are
genetically identical
phenocopies
→ environmental factors that give rise to disorders similar to
those of genetic disorders)
⑧
, 6 7
MENDELIAN GENETICS HUNTINGTON 'S DISEASE
÷÷÷÷ .÷ f÷ ÷ ÷ ÷ ÷ ÷ ÷
-
:::
Differences in conspecifics
-
Dominant allele has debilitating effects
-
↳ members of the same
species ↳
progressive disorder characterized by motor
: " ""
↳ only expressed when
previous generations -
HTT
gene codes for huntingtin protein
are carriers and new
generation doesn't ↳ mutation leads to production of abnormally long
dominant trait
carry protein
phenotype
-
that bind
↳ cut into smaller
fragments together
↳
andacaemulateinneurcf-G-enotyp.ee
observed traits
PHENYLKETONURIA
#
CDKU)
/ /
-
↳ transmitted traits
genetically
In.IO?yTi:T:.::omc::m7nan7?rece.iue rmeaemssriuaen.gueeecausesaaayeacoonin.ve
-
,
-
-
Homozygous : RR (dominant + dominant) / ↳
patients miss enzyme that's needed for
rrcrecessivetrece.si# phenylalanine Camino acid)
breaking down
↳ found in food
-
-
CHROMOSOMES AND INHERITANCE #
f÷ ÷ ÷ ÷
Meiosis
-
Genes are located
-
on chromosomes
↳ ↳ cell division
chromosomes are constructed from DNA
strands
↳ diploid cells turn into haploid gametes
↳ 23 base pairs; UG chromatids sperm meiosis
-
↳ 23 chromosome pairs are duplicated
}
22 autosomes
-
↳ divides ' duplicated chromosomes indifference
-
I}radp%!! dieferanbertowmoenomseees Karotype
↳ chromosomes are separated ,
cell divides again
↳ x and y
↳ haploid gamete
Egg meiosis
-
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.
"
↳ Long arm ↳ results in 46 chromosomes
-
Telomeres ↳
diploid zygote
repeated Mitosis
↳
genetic sequences at the
-
end of the arms ↳ diploid cell doubles chromosomes and divides
Cytogenetic bands
-
crossing
-
↳ stripes on chromosomes over
↳ source of genetic variation during meiosis
Diploid 23 pairs
-
set of chromosomes : ↳ while chromosomes duplicate , the chromatids
Haploid : one set of chromosomes
and sometimes break and
-
cross over eachother
Ggametesswapsit.es#
, 11
do
DNA WHAT IS DNA ?
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÷÷÷÷÷÷÷:÷÷÷ :÷: :÷f
-
Desoxy ribonucleic acid -
Each chromosome is made up of two DNA strands
::::
'
During DNA
replication two strands nucleotide bases ( adenine ,
-
the →
,
unravel cytosine , guanine and thymine)
↳
unravelled strand attracts unattached
-
strands are hold together by nucleotide base bonds
cytosine iauanines
Aaoduenbienenaihymine ;
-
/ endsthatconnedtoeachot#
,
l and five prime CS )
'
three
'
Mutations prime
-
-
↳ errors in replication
PROTEIN SYNTHESIS
13 14
GENETIC VARIATION
÷: ÷ ÷ :÷ ÷ ÷ ÷ :y÷ ÷
- -
:÷ ÷ ÷f
-
Nucleotide bases -
basic elements of code
Polymorphism
.
-
↳ code for construction of amino acids
↳ differences in DNA
sequences among
↳ amino acids make up enzymes proteins and
,
individuals
polypeptides ↳ often weak or no effect
codon of nucleotide
triplet
-
=
↳
single base pair of nucleotides is
↳ code is based on a
sequence of codons
↳
sequences that code for
proteins -
:÷ ÷ ÷ ÷ ÷ ÷ ÷ :÷i÷
Mutation
-
introns ↳ change in a single gene
↳ non -
coding sequences ↳ rare ,
random ,
and independent of
↳ mRNA removes introns the
organism 's needs
↳ can cause the disorder itself
Translation
-
↳ Mendelian pattern of
usually
↳ starts with start codon
inheritance
↳ Amino acids are taken to ribosomes by
transfer ribonucleic acid Ct RNA)
↳ ribosome reads codons and tRNA adds
amino acids
↳
Stop codon finishes
↳ Amino acid sequence goes on to make
I I
proteins , etc .
r
gem:: :::
-
; mauer ones
.
creatingmulhipleproteinsfromone.ge