MLT Clinical Chemistry Final Exam Questions and Answers

MLT Clinical Chemistry Final Exam Questions and Answers Enzymes that can bind only one substrate and catalyze one reaction exhibit which type of binding specificity? Answer > Absolute binding The rate of an enzymatic reaction will ___________________ for every 10 degrees C temperature increase until the enzyme denatures. Answer > Double All of the following conditions may result in a rise in CKBB levels except. a. Child birth b Spinal chord injury c. Myocardial infarction d. Brain tumor Answer > c. Myocardial infarction Which two enzymes will show significant elevations with viral hepatitis? Answer > AST & ALT GGT is an enzyme that can be used to help monitor the tr eatment of which patient population? Answer > recovering alcoholics Digestive enzymes circulate in inactive forms called __________________. Answer > Zymogens A patient comes to the ER with abdominal pain, the physician ordered an amylase, lipase, and lipid panel. The triglyceride result is significantly elevated, how might this effect the amylase and lipid levels? (thrown out) Answer > Unchanged lipase, decre ased amylase Which of the following is a function of glucose -6-phosphate dehydrogenase (G6PD) a. prevents RBC lysis b. inhibits CK c. stimulates insulin secretion d. catalyzes the conversion of glutamate Answer > a. prevents RBC lysis Which type of enz yme kinetics assay is ideal fro the clinical laboratory setting where the amount of enzyme produced by the patient is unknown? Answer > zero order What condition is characterized by elevated serum amylase levels and decrease urinary amylase levels due t o amylase binding to immunoglobulins? Answer > macroamylasemia In the presence of a competitive inhibitor, what would need to be increased to reach VMax? Answer > substrate A grossly hemolyzed sample is received in the lab, what effect would this hav e on the total CK determination? Answer > Falsely increased A patient with osteitis deformans would be expected to have elevations in which enzyme? Answer > ALP Which enzyme may be useful in diagnosing metastatic carcinomas of the prostate? Answer > ACP Which enzyme is most specific for the diagnosis of acute pancreatitis? Answer > Lipase