Pharmacology - Exam 1 Ameritech Questions + Answers Graded A+

Absorption - Movement of drug from site of administration to various tissues of the body Additive Effect - 1+1=2, Alcohol+Opioids= Fatal CNS depression Adverse Effects - Unintended effects of drugs that are more severe and can be life threatening. Agonist - Drugs that bind with receptor and precipitate greater than typical response. Allergic Reaction - Most severe type of adverse reaction. Severity range: itching, rash, hives, anaphylactic shock. Anaphylaxis - Exaggerated response of the body's immune system to a drug. Precipitates massive release of histamine and other chemical mediators. Antagonist - Drugs that bind with receptor and block response or less that typical response. Antagonistic Effect - 1+1=<2, Bioavailability - Amount of drug available after passing through the liver. 100% of drug!! Biotransformation - Change that occurs in a drugs chemical nature. Brand Name - Registered trademark of the drug, Capitalized Contraindication - Have potential to cause serious or life threatening adverse effects. Occurs in certain populations or in combination with other drugs and certain foods.Cumulative Effect - When amount of drug pt receives is greater than the rate it's excreted. Decreased functioning of the liver and kidneys would result in _________ of the half life of the drug. - Increase Distribution - Movement of drug by circulatory system to intended site of action