Chapter 1: Introduction to Pathophysiology
Test Bank
TRUE/FALSE
1. Normal ranges for physiologic parameters are arbitrarily defined based on population sampling.
ANS: T
2. Values outside the normal range for a particular variable are always indicative of disease.
ANS: F
3. Illness and disease always coexist.
ANS: F
4. Normalcy is culturally defined.
ANS: T
5. A change in a physiologic variable is more significant than the absolute values.
ANS: T
6. Most homeostatic mechanisms function via positive feedback loops.
ANS: F
7. Homeostatic control mechanisms function primarily during disease states.
ANS: F
8. Epidemiology is the study of disease expression in individuals.
ANS: F
9. The etiology and pathogenesis of most disease states have been well defined by research.
ANS: F
10. Individuals experiencing the same disease process exhibit the same clinical manifestations.
ANS: F
, MULTIPLE CHOICE
1. C.Q. was recently exposed to group A hemolytic Streptococcus and subsequently developed a
pharyngeal infection. His clinic examination reveals an oral temperature of 102.3° F, skin rash,
and reddened throat mucosa with multiple pustules. He complains of sore throat, malaise, and
joint stiffness. A throat culture is positive for Streptococcus, and antibiotics have been prescribed.
The etiology of C.Q.’s disease is
a a sore throat.
.
b streptococcal infection.
.
c genetic susceptibility.
.
d pharyngitis.
.
ANS: B
2. Which of the following is a statement about disease pathogenesis?
a Pharyngitis is caused by group A hemolytic Streptococcus infection.
.
b Streptococcal infection activates immune cells, leading to inflammation.
.
c Sore throat and mucosal inflammation are common signs and symptoms of pha-
. ryngeal infection.
d Antibiotics are the treatment of choice for streptococcal infection.
.
ANS: B
3. Which of the following assessment findings indicates an alteration in homeostatic control
mechanisms?
a Fever
.
b Throat pain
.
c Joint stiffness
.
d Positive throat culture
.
ANS: A
4. Most homeostatic mechanisms function on a negative-feedback principle, which facilitates
a minimal response to environmental changes.
.
, b an amplified response.
.
c a rapid response rate.
.
d steady-state stability.
.
ANS: D
5. A 17-year-old college-bound student receives a vaccine against an organism that causes
meningitis. This is an example of
a primary prevention.
.
b secondary prevention.
.
c tertiary prevention.
.
d disease treatment.
.
ANS: A
6. An obese but otherwise healthy teen is given a prescription for a low-calorie diet and exercise
program. This is an example of
a primary prevention.
.
b secondary prevention.
.
c tertiary prevention.
.
d disease treatment.
.
ANS: B
7. A patient with high blood pressure who is otherwise healthy is counseled to restrict sodium
intake. This is an example of
a primary prevention.
.
b secondary prevention.
.
c tertiary prevention.
.
d disease treatment.
.
ANS: B
, 8. After suffering a heart attack, a middle-aged man is counseled to take a cholesterol-lowering
medication. This is an example of
a primary prevention.
.
b secondary prevention.
.
c tertiary prevention.
.
d disease treatment.
.
ANS: C
MATCHING
Match the following terms with the descriptions below (not all letters will be used).
a Idiopathic
.
b Iatrogenic
.
c Morbidity
.
d Syndrome
.
e Sequela
.
f. Remission
g Complication
.
h Exacerbation
.
i. Subclinical
j. Endemic
k Pandemic
.
l. Etiology
m Epidemic
.
n Epidemiology
.
1. The conditions or illnesses associated with a disease
2. A set of symptoms that occur together
3. A disorder of unknown cause
4. An abatement or decline in disease manifestations
5. A disease that is continuously present in a particular region