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Summary Essential Notes: Gastrointestinal Medicine: GI Bleed

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Upper GI Bleed Lower GI Bleed
Upper GI bleed presents with:
 Haematemesis
Colonic bleeding bright red/dark red blood per rectum
 Malaena Blood in colon has a strong laxative effect  rarely retained
 Epigastric discomfort long enough for transformation into malaena
 Sudden collapse
Oesophageal bleeding Right-sided bleeds = darker coloured blood > Left-sided
 Oesophagitis small volume, fresh blood, often streaking vomit, malaena (rare),
often ceases spontaneously, usually Hx of GORD- type symptoms
 Cancer small volume of blood, except as pre-terminal event w/erosion of major Colitis brisk bleeding, diarrhoea, AXR- featureless colon
vessels, associated w/ dysphagia + weight loss, recurrent until malignancy Mx
 Mallory-Weiss tear brisk, small  moderate volume of blood, bright red blood 
Diverticular disease- acute diverticulitis  sporadic bleeds,
following repeated bout of vomiting 75% will cease w/i 24-48hrs, bleeding = dark + large volume
 Varices large volume of fresh blood, swallowed blood malaena, haemodynamic
compromise
Gastric bleeding Cancer bleed (1st sign)
 Gastric cancer frank haematemesis/altered blood mixed w/ vomit
Prodromal features- dyspepsia + constitutional erosion of vessels  haemorrhage
 Dieulafoy lesion no prodromal prior to malaena + haematemesis Haemorrhoidal bright red bleeding post-defecation, rarely
AV malformation  haemorrhage, difficult to detect endoscopically
 Diffuse erosive gastritis haematemesis + gastric discomfort
cause haemodynamic compromise
Recent NSAID use, large volume haemorrhage + haemodynamic compromise
 Gastric ulcer small low volume bleeds common  IDA, erosion  haematemesis +
haemorrhage
Angiodysplasia R > L
Duodenum
Major haemorrhage  posterior sited duodenal ulcer
Haematemesis + malaena + epigastric discomfort
Mx
Pain occurs several hours after eating Haemorrhoids- proctosigmoidoscopy
Upper GI Bleed Mx
Angiodysplasia- angiogram (CT/percutaneous)  performed
1. Admission, cross-match, check FBC, LFTs, U&Es + clotting (minimum) during period of haemodynamic instability  show bleeding
2. Pts w/ on-going bleeding + haemodynamic instability  O’ negative blood
3. Varices  Terlipressin prior to endoscopy  banded/sclerotherapy/ Sengaksten-
point  show patch of angiodysplasia
Blakemore tube  balloon inflation  deflating after 12h to prevent necrosis Otherwise colonoscopy
4. Upper GI bleed  Endoscopy w/i 24h
5. Pts w/ erosive oesophagitis/gastritis  PPI
UC? Sub-total colectomy
6. Mallory-Weis  resolves spontaneously
Indications for surgery
 Pts > 60 yrs
Indications for surgery
 Continued bleeding despite endoscopic intervention  Pts > 60 yrs
 Recurrent bleeding
 Known CVD w/ poor response to hypotension
 Continued bleeding despite endoscopic intervention
Duodenal ulcer  laparotomy, duodenotomy + under-running of ulcer  Recurrent bleeding
Gastric ulcer  under-running of bleeding site, partial gastrectomy-antral ulcer, total
gastrectomy if bleeding persists
 Known CVD w/ poor response to hypotension
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