Pharmacotherapy Principles and Practice Newest Update Questions With Elaborated Answer

Pharmacotherapy Principles and Practice Newest Update Questions With Elaborated Answer Clinical situation (type of pain), Cost, pharmacokinetics profile of available drugs, Patient specific factors (Age, concomitant illnesses, previous response, and other medications) must be considered. Management in absence of pain needs to be anticipated like in pre surgery. - ANSWER For initial pain therapy these guidelines can be useful? Mild pain - ANSWER 1-3 on pain scale. Who recommends nonopioid analgesic reg sch dose like Tylenol 1000 mg q 6 hrs or Motrin 600 q 6 hrs, consider adjunt if pain is not reduced in 1-2 days is? Moderate pain - ANSWER 4-6 on pain scale Who recommends ass opioid to the nonopioid for this pain, example is tyl 325 mg + codeine? Severe Pain - ANSWER 7-10 on the pain scale, Who recommends switch to high potency opioid reg scheduled dose? Nonselective (they inhibit COX-1 and COX-2) or selective (Inhibit only COX 2) based on degree of COX inhabitation. COX 2 is for inflammatory effect. COX 1 inhabitation contributes to increased GI and renal toxicity associated with nonselective agents. - ANSWER What is the mechanism of NSAIDs use?