UAMS MLT-MLS Comprehensive Exam | Latest Update | 2024/2025 | Graded A+

UAMS MLT-MLS Comprehensive Exam | Latest Update | 2024/2025 | Graded A+ What are whole blood transfusions used for? Cells and volume What are packed RBC transfusions used for? Anemia What are Washed RBC transfusions used for? Allergy to plasma proteins in IgA deficiencies What are Leuko-depleted RBC transfusions used for? Febrile from HLA or CMV risk What are Frozen, deglycerolized RBC transfusions used for? Rare or autologous What must be done to issue red cell products? ABO, Rh and screening compatible How are PLTs and WBCs stored? RT What are Leuko-reduced PLT or WBC transfusions used for? Prevent febrile from HLA and prevent CMV What are granulocyte transfusions used for? Severe neutropenia What are FFP transfusions used for? Coag disorders (type compatible) What are cryo transfusions used for? Factor VIII and IX concentrate- Virus inactivated and lyophilized What does PT monitor? Coumadin What will a cold agglutinin not affect on the cell counter? Hemoglobin What does Protein C deficiency cause? Thrombosis What does Factor XII deficiency cause? Thrombosis instead of bleeding How does old blood affect the RBCs and WBCs? Crenate RBCs and cause vacuoles in WBCs. What happens when you mix patient plasma (with a high PTT) with normal plasma? Corrects Factor Deficiency (Not correct lupus anticoagulant) Sickle cells and spherocytes will ____ a sed rate. Lower Patient with polycythemia needs to have anticoagulant adjusted for ___ or ____ PT or PTT 90% of the hemoglobin is Hgb C and the rest A2 and F on electrophoresis. Hgb C disease Associated with hyper-segmented neutrophils, pancytopenia and macrocytes. Megaloblastic anemia What are Howell-jolly bodies made up of? DNA fragments When are Howell-Jolly Bodies seen? Non-function spleen & accelerated or abnormal erythropoiesis What is basophilic stippling made up of? Denatured RNA When is basophilic stippling seen? Lead poisoning & thalassemia What are pappenheimer bodies (Siderocytes) made up of? mitochondria and ribosomes that contain iron When are pappenheimer bodies (Siderocytes) seen? Sideroblastic anemia, thalassemia, splenectomy When are Heinz bodies seen? G6PD deficiency, unstable hemoglobin causing iron to be unprotected, oxidizing drugs, alpha thalassemia What are Heinz bodies made up of? Denatured hemoglobin When are Cabot rings seen? Severe anemias, pernicious anemia, dyserythropoiesis What are Cabot rings made up of? arginine-rich histone and non-hemoglobin iron