MLT-MLS UAMS Hematology Exam 6 Questions and Answers | Latest Update | 2024/2025 | Already Passed

MLT-MLS UAMS Hematology Exam 6 Questions and Answers | Latest Update | 2024/2025 | Already Passed A deficiency of Protein C is associated with ... Increased risk of thrombosis A hospitalized patient on Coumadin has consistently had Protimes of 19-20 secs a) Is this what is expected? b) On a given day, the same patient has a protime of 11.4 sec. What is the best course of action? Yes; redraw sample (probably wrong patient) or poor venipuncture A patient presents with an aPTT of 49seconds (25-35 seconds). A mixing study is perfomred with the following results: Patient plasma mixed 1:1 with normal pooled plasma: 45 seconds Control- Normal Pooled Plasma PTT: 32.0 seconds These results indicate: Circulating Anticoagulant A sample of blood was drawn out of a central line. The PT and PTT are high before anticoagulation therapy. What would you recommend? Drawing the sample. If line is used, flush with 5 ml of saline and discard those 5 mls first. Activated factors act as... enzymes Adhesion A reversible characteristic in which platelets roll and cling to non-platelet surfaces ADP causes arachidonic acid to form what? Thromboxane A2 Alpha granules contain... Factors I, V, and vWF Barium sulfate absorbs which factors? (4) II, VII, IX, X Bleeding Time normal range 2-9 mins D-Dimer normal range <0.5 mcg/mL Deficiencies in coag inhibitors cause... thrombosis Dense platelet granules contain... (3) ADP, Calcium, and serotonin During fibrinolysis, plasminogen is converted to... Plasmin Endomitosis doubling of DNA without cell division Explain the thrombin time test. When will it be prolonged? Directly measures the conversion of fibrinogen to fibrin, which is cleaved by thrombin; bypasses the cascade; heparin therapy will cause a prolonged thrombin time, dysfibrinogemia, DIC Explain what is the INR? Formula? Standardization of PT reagents by looking at sensitivity index of reagents. INR= PT(patient)^isi/PT(normal) Fibrinogen normal range 200-400 mg/dL Fibrinolysis Enzyme dissolution of fibrin clot after healing Give an example of an inherited vascular disorder. Hereditary telangiectasia Glycoprotein Ib is the binding site for... vWF Glycoprotein Ib/IV/V binds with vWF Glycoprotein IIb/IIIa binds to fibrinogen Glycoprotein IIb/IIIa is involved with platelet... aggregation