UNE BIOCHEM 1005 FINAL EXAM
2024 UPDATE [MOST TESTED AREAS]
QUESTIONS WITH CORRECT VERIFIED
ANSWERS ALL PASSED GRADE A+
The alanine - glucose cycle is primarily used for which of the following
purposes?
a. To move ammonia from skeletal muscle to the liver
b. To generate ATP for the skeletal muscle
c. To move glucose from the skeletal muscle to the liver
d. To move alanine from the liver to the skeletal muscle - (correct
answer) a. To move ammonia from skeletal muscle to the liver
Which statement best illustrates an example of post translational gene
regulation?
a. Protein kinase A mediated phosphorylation of glycogen
phosphorylase
b. Cortisol binds a cytosolic receptor, translocates to the nucleus and
binds a GRE
c. Iron binding the iron response elements binding protein (IRE_BP)
allowing for translation of ferritin mRNA
,d. DNA histone associations leading to super-coiling of DNA - (correct
answer) a. Protein kinase A mediated phosphorylation of glycogen
phosphorylase
Somatostatin reduces the secretion of both glucagon and insulin
through which of the following mechanisms?
a. Somatostatin activates an activator G-protein
b. Somatostatin activates MAPK cascade
c. Somatostatin activates an inhibitory G-protein
d. Somatostatin uses Ca+2 as a downstream signal - (correct answer)
c. Somatostatin activates an inhibitory G-protein
Insulin mediated glucose uptake by muscle and adipose tissue is a
result of which of the following mechanisms?
a. Translocation of GLUT 4 receptors to the cell surface
b. Translocation of GLUT 1 (Na+/K+ symporter) to the cell surface
c. Passive diffusion
d. Activation of protein kinase A - (correct answer) a. Translocation
of GLUT 4 receptors to the cell surface
Which of the following hormones is released from the liver in response
to increased levels of growth hormone?
,a. Cortisol
b. Thyroid hormone
c. Somatostatin
d. Insulin-like growth factor (IGF) - (correct answer) d. Insulin-like
growth factor (IGF)
Autophagy is process involves degradation of protein. Under conditions
of high energy (HIGH ATP) which of the following is true regarding
regulation of this process?
a. Akt is inactive
b. AMPK is actice and phosphorylates TSC1/TSC2 Complex
c. mTOR is activated
d. Rheb is bound to GDP - (correct answer) c. mTOR is activated
Synthesis of which of the following lipoproteins would be elevated after
a carbohydrate rich meal?
a. HDL
b. Chylomicrons
c. LDL
d. VLDL - (correct answer) d. VLDL
, The synthesis of N-acetylglutamate (NAGS) is required for the activity of
the urea cycle. This compound stimulates the activity of which of the
following enzymes?
a. Arginase
b. Carbamoyl phosphate synthetase I (CPSI)
c. Ornithine transcarbamoylase
d. Carbamoyl phosphate synthetase II (CPSII) - (correct answer) b.
Carbamoyl phosphate synthetase I (CPSI)
A male infant starts to show signs of lethargy rapidly after birth. Upon
evaluation he is determined to have a deficiency in n-acetylglutamate
synthesis. Based on this information, which of the following would
consistent with this diagnosis?
a. Elevated levels of arginine
b. Decreased levels of carbamoyl phosphate
c. Decreased levels of ammonia
d. Elevated levels of citrulline - (correct answer) b. Decreased levels
of carbamoyl phosphate
Which of the following individuals would most likely be in a positive
nitrogen balance?
2024 UPDATE [MOST TESTED AREAS]
QUESTIONS WITH CORRECT VERIFIED
ANSWERS ALL PASSED GRADE A+
The alanine - glucose cycle is primarily used for which of the following
purposes?
a. To move ammonia from skeletal muscle to the liver
b. To generate ATP for the skeletal muscle
c. To move glucose from the skeletal muscle to the liver
d. To move alanine from the liver to the skeletal muscle - (correct
answer) a. To move ammonia from skeletal muscle to the liver
Which statement best illustrates an example of post translational gene
regulation?
a. Protein kinase A mediated phosphorylation of glycogen
phosphorylase
b. Cortisol binds a cytosolic receptor, translocates to the nucleus and
binds a GRE
c. Iron binding the iron response elements binding protein (IRE_BP)
allowing for translation of ferritin mRNA
,d. DNA histone associations leading to super-coiling of DNA - (correct
answer) a. Protein kinase A mediated phosphorylation of glycogen
phosphorylase
Somatostatin reduces the secretion of both glucagon and insulin
through which of the following mechanisms?
a. Somatostatin activates an activator G-protein
b. Somatostatin activates MAPK cascade
c. Somatostatin activates an inhibitory G-protein
d. Somatostatin uses Ca+2 as a downstream signal - (correct answer)
c. Somatostatin activates an inhibitory G-protein
Insulin mediated glucose uptake by muscle and adipose tissue is a
result of which of the following mechanisms?
a. Translocation of GLUT 4 receptors to the cell surface
b. Translocation of GLUT 1 (Na+/K+ symporter) to the cell surface
c. Passive diffusion
d. Activation of protein kinase A - (correct answer) a. Translocation
of GLUT 4 receptors to the cell surface
Which of the following hormones is released from the liver in response
to increased levels of growth hormone?
,a. Cortisol
b. Thyroid hormone
c. Somatostatin
d. Insulin-like growth factor (IGF) - (correct answer) d. Insulin-like
growth factor (IGF)
Autophagy is process involves degradation of protein. Under conditions
of high energy (HIGH ATP) which of the following is true regarding
regulation of this process?
a. Akt is inactive
b. AMPK is actice and phosphorylates TSC1/TSC2 Complex
c. mTOR is activated
d. Rheb is bound to GDP - (correct answer) c. mTOR is activated
Synthesis of which of the following lipoproteins would be elevated after
a carbohydrate rich meal?
a. HDL
b. Chylomicrons
c. LDL
d. VLDL - (correct answer) d. VLDL
, The synthesis of N-acetylglutamate (NAGS) is required for the activity of
the urea cycle. This compound stimulates the activity of which of the
following enzymes?
a. Arginase
b. Carbamoyl phosphate synthetase I (CPSI)
c. Ornithine transcarbamoylase
d. Carbamoyl phosphate synthetase II (CPSII) - (correct answer) b.
Carbamoyl phosphate synthetase I (CPSI)
A male infant starts to show signs of lethargy rapidly after birth. Upon
evaluation he is determined to have a deficiency in n-acetylglutamate
synthesis. Based on this information, which of the following would
consistent with this diagnosis?
a. Elevated levels of arginine
b. Decreased levels of carbamoyl phosphate
c. Decreased levels of ammonia
d. Elevated levels of citrulline - (correct answer) b. Decreased levels
of carbamoyl phosphate
Which of the following individuals would most likely be in a positive
nitrogen balance?
