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Advanced Pathophysiology midterm

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1. Endoplasmic reticulum protein folding occurs 2. Lysosomes needed for digesting and defense 3. mitochondria ATP cellular respiration 4. Nucleolus Where RNA transcription occurs 5. Nucleus contains DNA 6. peroxisomes detoxifies fatty acids 7. Ribosomes transport proteins and begin protein synthesis

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Advanced Pathophysiology midterm



1.

Endoplasmic

reticulum

protein folding occurs

2.

Lysosomes

needed for digesting and defense

3.

mitochondria

ATP cellular respiration

4.

Nucleolus

Where RNA transcription occurs

5.

Nucleus

contains DNA

6.

peroxisomes

detoxifies fatty acids

7.

Ribosomes

transport proteins and begin protein synthesis

8.

,What is the result

of glycolysis

2 molecules of ATP and 2 molecules of pyruvate

9.

Oxidative phosphorylation

The production of ATP using energy in the presence of

oxygen to convert pyruvate to acetyll co-A



10. anaerobic glycolysis

pyruvate is converted to lactic acid



11. where is most ATP synthesized?

in the mitochondria



12. what part of the cell communicates with other cells to promote migration?

the plasma membrane



13. Paracrine membrane contact

release of chemicals to cells close by



14. autocrine membrane contact

cells signal themselves

,Advanced Pathophysiology midterm



15. hormonal membrane communication

hormones act as chemical signals



16. neurohormonal membrane communication

neurons release neurotransmitters that travel in the blood

vs a synapse



17. what are examples of hormonal processes mediated by cAMP

epinephrine

ACTH

glucagon

ADH

thrombin



18. secondary messengers

involved in cell signaling

- ligand binds to a receptor, signals cAMP or ca++



19. hypoxic injury

results from lack of O2, leads to DNA damage



20. what do reactive oxygen species result in

increased cell damage and deah

, 21. what is tonicity

the osmotic force exerted by molecules like sodium and

albumin



22. isotonic fluid deficit S/s and labs

dehydration



23. isotonic fluid excess s/s and labs

hypervolemia, low H, hyponatremia, edema, pulmonary edema, HTN



24. Na+ lab value

135-145 mEq/L



25. K+ lab value

3.5-5.0 mEq/L



26. Ca+ lab value

8.5-10.5 mg/dL



27. Mg+ lab value

1.5-3 mg/dL



28. what electrolytes are effected by kidney failure?

increased serum and potassium, magnesium, and phosphare



29. What does aldosterone promote

sodium retention and potassium excretion
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