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Summary Gastrointestinal tract drugs summarised in a table

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19-06-2019

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I will soon have my Masters in Genetics and I completed my honours in Clinical Pharmacology. The pharmacology was course work on it's own, so the summaries are very well written and easy to learn. If you have Pharmacology, you will know that it is a lot of work to get in your mind in a short amount of time. I want to help you get through all the drug classes.

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Connected book

Humphrey Rang, James M. Ritter Rang & Dale\'s Pharmacology

Edition:januari 2015
ISBN:9780702053627
Edition:1

Written for

Institution: University of Pretoria (UP)
Course: Pharmacology (FAR382)

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Document information

Summarized whole book?: Yes
Uploaded on: June 19, 2019
Number of pages: 2
Written in: 2014/2015
Type: Summary

Subjects

pharmacology
far 381
far 382
pharmacodynamics
pharmacy
pharmacokinetics

Content preview

Ionisation
IONISED
 POLAR
 Water-soluble
 Lipophobic
 Hydrophilic
 Do not cross membranes readily

 ACIDIC drugs bind to ALBUMIN
 ACIDS are ionised in BASIC media

 BASIC drugs bind to α1-GLYCOPROTEIN
 BASES are ionised in acidic media

UNIONISED
 NON-polar
 Fat soluble
 Hydrophobic
 Lipophilic
 Diffuse more readily across a membrane
 Very HIGH L-WDC
 Distributes widely through the body
 Acts in the CNS (crosses the bbb by PASSIVE DIFFUSION)

Weak ACIDS
HA  A- + H+
¿ IONISED
 pH= pKa + log10 A− HA ¿ Ratio = UNIONISED
With a dissociation constant K
a

Weak BASES
BH+  B + H+

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Summary Gastrointestinal tract drugs summarised in a table

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