MGCCC Nursing Pharmacology Review Questions with Answers

Sulfamethoxazole-Trimethoprim/TMP-SMZ (Actions) Inhibit bacterial synthesis of folic acid Bacteriostatic Fights gram - bacteria Proteus, Klebsiella, E. coli, Chlamydia Sulfamethoxazole-Trimethoprim/TMP-SMZ (uses) Otitis media, respiratory infections UTIs, prostatitis, gonorrhea Sulfamethoxazole-Trimethoprim/TMP-SMZ (Routes) Oral, IV, topical, ophthalmic Sulfamethoxazole-Trimethoprim/TMP-SMZ (Contraindications) Br feeding infants <2mo. Hypersensitivity, term pregnancy, megaloblastic anemia, chancroid, traveler's diarrhea Sulfamethoxazole-Trimethoprim/TMP-SMZ (Side Effects) Mild to moderate rash, photosensitivity GI distress, stomatitis, crystalluria Fatigue, depression, headache, dizziness Sulfamethoxazole-Trimethoprim/TMP-SMZ (Adverse Reactions) Blood dyscrasias Stevens-Johnson syndrome Renal failure Sulfamethoxazole-Trimethoprim/TMP-SMZ (Nursing Interventions) Administer with full glass of water 1 hour before meals or 2 hours after meals. Increase fluid intake. Monitor for sore throat, bruising, bleeding. Monitor CBC. Check for superinfection. Advise client not to take with antacids. Tell client to avoid direct sunlight. Use alternate forms of OCP Avoid OTC (asa, vit.C) Sulfamethoxazole-Trimethoprim/TMP-SMZ (Drug Interaction) Warfarin Increases anticoagulation Oral hypoglycemic Increases hypoglycemia