PHRM 845 || All Questions Answered Correctly.

When you accidentally step onto a sharp object you retract your foot via Adelta-fibers, because they are the fastest firing nerves. A. The statement and rationale are true B. The statement is true, but the rationale is false C. The statement is false correct answers B. The statement is true, but the rationale is false Adelta fibers are the nerves controlling the reflex arc, but they are not the fastest firing nerves. Abeta are faster for example A patient reports to the pharmacist to pick up a prescription for a painkiller to alleviate pain from nerve damage caused by a traffic accident. Which of the following drugs is the least likely to have been prescribed? A. An agonist of mu opioid receptor B. An antagonist of acid sensing ion channels C. A calcium channel antagonist D. A NMDA receptor antagonist correct answers B. An antagonist of acid sensing ion channels ASIC channels are located in the periphery and are not expected to play a role induced by nerve damage. A patient cut deeply into his thumb while cooking. After receiving stitches at the ER, the next day the patient goes to the local pharmacy for a painkiller for the throbbing pain he experiences. Which of the following statements is true? A. The current pain the patient describes is a sign of chronic pain. B. The current pain originates from C-fiber signaling. C. The current pain originates from Adelta fibers. D. Throbbing pain means the patient severed nerves. correct answers B. The current pain originates from C-fiber signaling. It is too early to describe this as chronic pain (>3 continuous months). The Adelta fibers provided the initial painful signal when the patient cut himself, the c-fiber then more slowly produces the secondary pain signals. Stabbing pain does not necessarily equate to inflammatory pain. Based on your knowledge of its etiology, which of the following could reduce the effects of central sensitization? A. A sodium channel agonist B. NMDA receptor antagonist C. Neurokinin (SP) receptor agonist D. An anti-histamine correct answers B. NMDA receptor antagonist Central sensitization is driven by increased substance P and BDNF in the spinal cord. Leading to an upregulation of NMDA/AMPA receptors, this can be blocked with a NMDA receptor