Aspirin and Acetaminophen || All Questions Answered Correctly.

aspirin correct answers acetylsalicylic acid mechanism of action (MOA) of aspirin correct answers irreversible acetylation of sarin at cycloxygenase how is aspirin absorbed? correct answers rapidly absorbed, peak level in 1-2 hours rapidly hydrolyzed what does aspirin deacetylate to? correct answers acetic acid and salicylate aspirin site of action? correct answers stops prostacyclin synthesis why is aspirin toxic? correct answers shifts from 1st order to 0 order how is aspirin eliminated? correct answers enzymatic hydrolysis, 1st order rate of elimination 0 order elimination correct answers its constant no matter what (like alcohol) 1st order elimination correct answers its half-life is always the same why is aspirin used? correct answers preventing cardiac attacks; for pain fever, inflammation, platelet deposition reduced colon cancer primary prophylaxis of MI rheumatic fever, Kawasaki disease Aspirin as Analgesia correct answers Decreases PGE2 at inflammation sites, which lowers pain! relieves headaches due to muscle strain and to vascular impingement on dura Aspirin as Antipyretic correct answers hypothalamus sets normal temp limit, lowers fever! Aspirin as anti-platelet correct answers blocks COX in platelets and stops TXA2 synthesis A high dose of aspirin does what? correct answers blocks prostaglandin synthesis