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MPharm Y4 MP429 Workshop Notes

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Notes on every MP429 workshops, summary based on the given LIs

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Week 7: Workshop 1- New Medicines, Better Medicines, Better Use of Medicines (The
Patient, The Medicine, The Pharmacist)


AIMS
• To understand the different types of information sources available in pharmacy
practice.
• To obtain information from primary literature sources and apply them to a health
topic.
• To gain familiarity with the range of research conducted within SIPBS and its
relevance to patient care.

LEARNING OUTCOMES
At the end of this workshop, you should:
• ☒Be familiar with the range of research performed within SIPBS and its relevance
to patient care and pharmacy practice.
Achieved this by looking at papers in various research areas by SIPBS staff

• ☒Develop an awareness of primary literature sources.
I have become familiar looking and searching for information using them
I understand the structure of them and what type of information source they are
and what they will include

• ☒Be able to locate information contained within primary reference sources and
apply the information to problem solving.
Consider which section of the source you will find this info in
-Abstract -helps determine whether this resource is relevant, good summary of
study
If abstract relevant then read full text – as will hide limitations of their own study
etc
-Introduction – background of science involved in study

Applying information of information sources
-If able to answers questions about the paper
-Deciding if article is relevant? -consider could you apply this to your practice, or
carry out a similar study to see if relevant for your practice ie do you face similar
issues, or different but could apply the same principles


Notes
Don’t need to understand everything in the paper, or all the underlying science but
be able to extract the key and relevant points


Three types of information sources:

,-Primary – original information, researcher carried out study/experiment then
written up results

Ex -original research articles, case reports, patents

Include objectives, background, methodology, results, discussion and conclusion

Be aware of similarities when deciding what type of reference source it is
Ex- Study that used patient hospital records to get their results
THIS IS PRIMARY as they had to gather this information even though it wasn’t written
by the researchers themselves, there wasn’t a summary of multiple primary
reference sources (the def of secondary)

-Secondary Resources
Two types
-indexing and abstracting

Used to keep primary research sources ie pubmed, google scholar
Another type is to review and summarise findings of primary resources ie review
articles, meta analyses
Ex: review articles, evidence-based summaries, meta analyses

-Tertiary

Ex: monographs, handbooks ie Drug monographs (BNF), Stockleys
Pull information from primary and secondary
Give summary of information from secondary resources
Used to provide rapid access to information/evidence

Order to use when looking for info – tertiary then secondary then primary

Tertiary quicker to access, good summary
Secondary -information already gathered, increase reliability as evidence backed up
by multiple primary sources

,Weeks 7-8: Workshops 2, 3 & BAP lab2 – New
Medicines: Case studies and Assessment (The
Medicine)
AIM
This series of workshops aim to provide students the opportunity to investigate the
development journey of medicines from initial concept to clinical use. Working in small
groups students will process the data available from a drug and develop a new drug product.

LEARNING OUTCOMES
At the end of this workshop, you should be able to:

• ☐To understand the challenges and considerations involved in getting a new
medicine before the licencing body and into the clinic (First-in-class; best-in-class;
clinical need, clinical efficacy, economic need)

• ☐To understand how to organise and work within a team to successfully deliver
and achieve a predefined objective through collective responsibility




Notes

5 cases were covered over 2 workshops, and 1 lab, additional case for revision

-Case 1 Paliperidone Prolonged Release Tablet (Antipsychotic)

-Case 2 Prednisolone Tablet (Steroid)

-Case 3 Fentanyl Spray (Solution)

-Case 4

-Case 6 Nintedanib Capsule (TKI)



-We firstly had to identify the drug based on physiochemical and pharmacological data we
were given ie

, -After identifying we had to answer questions

These showed the importance of these properties in a drug being formulated in a particular
way

Examples of Qs:




-Also asked to identify role of excipients in drug

DEVELOP THESE NOTES!



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