BCPS Exam with Correct Solutions 2024

BCPS Exam with Correct Solutions 2024 anti htn of choice in pregnancy - Answer -methyldopa, labetolol AC of choice in pregnancy - Answer -enox n/v meds for pregnancy - Answer -pyridoxine, doxylamine, meclizine, dimenhydrainate avoid in breastfeeding - Answer -opioids, contrast (x3wks after), buproprion/varenicline combined hormonal contraception post partum - Answer -3 weeks if no risk factors, 6 weeks if risk factor early breakthrough bleeding vs late breakthrough - Answer -increase estrogen vs increase progestin (after at least 3 month trial) significant reduction in birth control efficacy know from - Answer -rifampin, anticonvulsants, lamotrigine (it is decreased by OC) antibiotics and OC - use backup method with . . . - Answer -don't have to have an alternate unless pt uncomfort or has breakthrough bleeding standard estrogen component in combined oral contraceptives - Answer -20-34 mcg progestone only pills - missed pill if taken how late? - Answer -3 hours infertility at <35, >35 - Answer -< 35 = 1 year of trying; > 35 = 6 mo treatment of HSV - initial infection - Answer -acclovir 400 mg PO TID x 7-10 d (only treats symptoms; virus doesn't go away) suppressive therapy for HSV infection - - Answer -acyclovir 400 mg PO BID or valacyclovir 500 mg po daily gonococcal infection treamtnet - Answer -treat for chlamydia too; ceftriax 250 mg IM x 1 plus azithro pelvic inflammatory disease - Answer -cefotetan 2 g IV q12h or cefoxitin 2 g iv q6h + doy - treat until clinical improvement bacterial vaginosis - treatments - Answer -metronidazole or clindamycin calculation for Risk ratio - Answer -RR = A/(A+B) / C/(C+D) Calculation for odds ratio - Answer -OR = A/C / B/D analysis used for discreet data - Answer -chi squared type of analysis used for continuous data - Answer -t-test, two sample if data is split into two groupscommon tests for heterogenity in meta-analyses - Answer -x2 or cochrane Q calculate number needed to treat - Answer -1/absolute risk reduction (only calculate if stastically significant difference found) osmolality of plasma, CNS fluid - Answer -270-300 mOsm/kg; 280-300 mOsm/kg max osmo of peripheral injections for no pain - Answer -> 900 injection pain and buring FD&C Act of 1938 - required proof of ? - Answer -safety (thalimide) Defauver-harris amendment of 1962 required proof of? - Answer -efficacy Generic drug pathway act was? - Answer -Hatch-Waxman Act - Drug price competition and patent term restoration acto f 1984 Durham-humphrey amendment of 1951 did what - Answer -established difference between Rx and nonrx SSRIs with greatest 2D6 inhibition - Answer -fluoxetine, paroxetine (very high) SSRIs with greatest 1A2 inhibition - Answer -fluvoxamine (high), fluoxemine (med