PSU Chem 210 Final Review Questions & Answers(Graded A)

E2 Reaction - ANSWEROne-Step with no intermediates, Base takes off proton + LG leaves with double bond formation. What type of carbons do E2 rxns favor? - ANSWERTertiary What is a Zaitsev product? - ANSWERDouble bond formation on more substituted carbon What is a Hoffman product? - ANSWERDouble bond formation on less substituted carbon When using a stericallly hindered base (t-BuOK, LDA), which product is more favorable? - ANSWERHoffman When using Eto- or less sterically hindered base, which product is more favorable? - ANSWERZaitsev E1 Reaction - ANSWER2 step process, LG leaves and forms carbocation, then base takes off proton and makes double bond What type of carbocations do elimination reactions prefer? - ANSWERTertiary What is the rate determining step of an E1 reaction? - ANSWERLG leaving What stereochemistry do E1 reactions usually want? - ANSWERTrans If the substrate is OH in a potential E1 reaction, what must be done before anything else? - ANSWERNeed a SA to protonate What makes a better nucleophile? - ANSWERLarge atoms What do halogens usually react as? - ANSWERNucleophiles What energy level does the electrophile contribute to? - ANSWERLumo What energy level does the nucleophile contribute to? - ANSWERHomo If OH is a leaving group, what can you convert it to? - ANSWERTsCl What are some good nucleophiles that aren't bases? - ANSWERCl-, Br-, I-, Hs-, H2s, RS-, RSH Wh