Unit 4C: Explore manufacturing techniques and testing methods for an organic solid

Unit 4C: Laboratory Techniques and
their Application
C: Explore manufacturing techniques
and testing methods for an organic solid




Anonymous
BTEC Level 3 Applied Sciences


INTRODUCTION:

, Aspirin is a generic term for acetylsalicylic acid. This substance was
first introduced in the late 1890s, that has become a ‘’non-steroidal anti-
inflammatory drug’’, non-opioid analgesic and antiplatelet drug which is
widely used for medicinal purposes. Aspirin will not react against the acetic
conditions of the stomach, yet it is hydrolysed in the intestines as it will
react on alkaline conditions to create ethanoate ions and salicylate.
Aim: In this practical, an Aspirin will be made by using laboratory
techniques and will identify the percentage yield and purity of the
substance.
Requirements:
Part 1
 salicylic acid – 6.02g
 100 cm3conical flask
 10 cm3 measuring cylinder
 ethanoic anhydride - 10cm3
 concentrated sulfuric acid in a dropping bottle
 400 cm3 beaker
 Tripod, gauze and Bunsen burner
 Thermometer (-10°C to 110 °C)
 250 cm3 beaker
 Reduced pressure filtration apparatus
 Filter paper
 Glass stirring rod
 Deionised or distilled water in a wash bottle
 Spatula
 pipette
Part 2
 25 cm3 measuring cylinder
 Boiling tube
 ethanol
 Thermometer (-10 °C to 110 °C)
 Deionised or distilled water in a wash bottle
 250 cm3 beaker
 100 cm3 conical flask
 Glass stirring rod
 A kettle