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BIOD_152_Final_Exa m Correct Answer

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BIOD_152_Final_Exa m Correct Answer Replication of DNA begins at a single origin of replication and then proceeds the entire length of the strand, in one direction (T/F) False What enzyme is responsible for relieving the stress associated with the twisting and untwisting of a DNA strand during replication. Topoisomerase As a replicated DNA strand elongates, what enzyme is responsible for adding nucleotides? DNA polymerase The energy required to add a nucleotide to a growing chain is supplied by an exergonic reaction involving the hydrolysis of the nucleotide's pyrophosphate tail (T/F) True During elongation, in which direction are new nucleotides being added to the leading strand? 5' —> 3' The leading strand requires ____ # of RNA primers, and the lagging strand requires ____ # of RNA primers. One; more than one What replaces RNA nucleotides with DNA nucleotides in a newly synthesized strand? DNA Polymerase A class of DNA polymerase patrols newly added nucleotides and will remove nucleotides that are erroneous. How does the polymerase "know" a nucleotide is misplaced. Newly adde nucleotides are compared to the complimentary template strand. Mismatch repair is the process of identifying nucleotides that are inappropriately matched, such as guanine with a thymine, and removes the incorrect nucleotide from the newly synthesized strand (t/f) True Nucleotide excision repair (cutting DNA) is accomplished by what enzyme? Nucleases Telomeres contain a large proportion of vital coding DNA (T/F) False What cells of the body are shielded from telomere shortening? Germ cells

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